CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035871
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pyruvate kinase 
Protein Synonyms/Alias
  
Gene Name
 pykF 
Gene Synonyms/Alias
 EAM_1657 
Created Date
 July 27, 2013 
Organism
 Erwinia amylovora (strain ATCC 49946 / CCPPB 0273 / Ea273 / 27-3) 
NCBI Taxa ID
 716540 
Lysine Modification
Position
Peptide
Type
References
317MLSGESAKGKYPLESacetylation[1]
319SGESAKGKYPLESVNacetylation[1]
Reference
 [1] Differential lysine acetylation profiles of Erwinia amylovora strains revealed by proteomics.
 Wu X, Vellaichamy A, Wang D, Zamdborg L, Kelleher NL, Huber SC, Zhao Y.
 J Proteomics. 2013 Feb 21;79:60-71. [PMID: 23234799] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Glycolysis; Kinase; Magnesium; Pyruvate; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 470 AA 
Protein Sequence
MKKTKIVCTI GPKTESEEML TNLLDAGMNV MRLNFSHGDY QEHGKRISNL RNVMNKSGHQ 60
AAILLDTKGP EIRTMKLEGG QDASLKAGQT FTFTTDQSVI GNADTVAVTY PGFTADLQVG 120
NTVLVDDGLI GMEVTAVTES TVVCKVLNNG DLGENKGVNL PGVSIQLPAL AEKDKLDLIF 180
GCEQGVDFVA ASFIRKRSDV IEIREHLKAH GGEHIQIISK IENQEGLNNF DEILDASDGI 240
MVARGDLGVE IPVEEVIFAQ KMMIKKCNHA RKVVITATQM LDSMIKNPRP TRAEAGDVAN 300
AILDGTDAVM LSGESAKGKY PLESVNIMAT ICERTDRVMK SRIDSQHDNR KMRITEAVCR 360
GAVETAEKLE APLIVVATEG GKSAKSIRKY FPNATILALT TNEQTSRQLL LSKGIITSVV 420
DKIASTDDFY RLGKAAAEAS GYAHKGEVVV MVSGALVPSG TTNTASVHVL 470 
Gene Ontology
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0030955; F:potassium ion binding; IEA:InterPro.
 GO:0004743; F:pyruvate kinase activity; IEA:EC.
 GO:0006096; P:glycolysis; IEA:UniProtKB-UniPathway. 
Interpro
 IPR001697; Pyr_Knase.
 IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
 IPR011037; Pyrv_Knase-like_insert_dom.
 IPR015794; Pyrv_Knase_a/b.
 IPR018209; Pyrv_Knase_AS.
 IPR015793; Pyrv_Knase_brl.
 IPR015795; Pyrv_Knase_C.
 IPR015806; Pyrv_Knase_insert_dom. 
Pfam
 PF00224; PK
 PF02887; PK_C 
SMART
  
PROSITE
 PS00110; PYRUVATE_KINASE 
PRINTS
 PR01050; PYRUVTKNASE.