CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010977
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L21-A 
Protein Synonyms/Alias
  
Gene Name
 RPL21A 
Gene Synonyms/Alias
 URP1; YBR191W; YBR1401 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
32VHLSTYLKVYKVGDIubiquitination[1]
35STYLKVYKVGDIVDIubiquitination[1]
43VGDIVDIKANGSIQKubiquitination[1, 2]
55IQKGMPHKFYQGKTGacetylation[3]
55IQKGMPHKFYQGKTGubiquitination[1]
60PHKFYQGKTGVVYNVacetylation[3]
60PHKFYQGKTGVVYNVubiquitination[1]
69GVVYNVTKSSVGVIIubiquitination[1]
78SVGVIINKMVGNRYLacetylation[3]
78SVGVIINKMVGNRYLubiquitination[1]
120AAKRAEAKAQGVAVQubiquitination[1, 2]
129QGVAVQLKRQPAQPRubiquitination[1, 2]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [3] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
  
Sequence Annotation
  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 160 AA 
Protein Sequence
MGKSHGYRSR TRYMFQRDFR KHGAVHLSTY LKVYKVGDIV DIKANGSIQK GMPHKFYQGK 60
TGVVYNVTKS SVGVIINKMV GNRYLEKRLN LRVEHIKHSK CRQEFLERVK ANAAKRAEAK 120
AQGVAVQLKR QPAQPRESRI VSTEGNVPQT LAPVPYETFI 160 
Gene Ontology
 GO:0022625; C:cytosolic large ribosomal subunit; TAS:SGD.
 GO:0003735; F:structural constituent of ribosome; TAS:SGD.
 GO:0002181; P:cytoplasmic translation; TAS:SGD. 
Interpro
 IPR001147; Ribosomal_L21e.
 IPR018259; Ribosomal_L21e_CS.
 IPR008991; Translation_prot_SH3-like. 
Pfam
 PF01157; Ribosomal_L21e 
SMART
  
PROSITE
 PS01171; RIBOSOMAL_L21E 
PRINTS