UniProt Accession

 D6RF95_HUMAN; D6RF95 

Genbank Protein ID

 AL118496; AL138968 

Genbank Nucleotide ID

  

Protein Name

 Long-chain-fatty-acid--CoA ligase 4 

Protein Synonyms/Alias

  

Gene Name

 ACSL4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
107	GLTALGLKPKNTIAI	ubiquitination	[1, 2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 154 AA 

Protein Sequence

Gene Ontology

 GO:0031966; C:mitochondrial membrane; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0005777; C:peroxisome; IEA:Compara.
 GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:Compara.
 GO:0060996; P:dendritic spine development; IEA:Compara.
 GO:0060136; P:embryonic process involved in female pregnancy; IEA:Compara.
 GO:0015908; P:fatty acid transport; IEA:Compara.
 GO:0070672; P:response to interleukin-15; IEA:Compara.
 GO:0007584; P:response to nutrient; IEA:Compara.
 GO:0006641; P:triglyceride metabolic process; IEA:Compara. 

Interpro

 IPR000873; AMP-dep_Synth/Lig. 

Pfam

 PF00501; AMP-binding 

SMART

  

PROSITE

  

PRINTS