| Tag | Content |
|---|
| CPLM ID | CPLM-014806 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Kazrin |
Protein Synonyms/Alias | |
Gene Name | Kazn |
Gene Synonyms/Alias | Kaz; Kiaa1026 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 115 | LEESQGGKCSEVLSA | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known. |
Sequence Annotation | DOMAIN 450 515 SAM 1.
DOMAIN 528 592 SAM 2.
DOMAIN 616 683 SAM 3.
MOD_RES 350 350 Phosphoserine.
MOD_RES 371 371 Phosphoserine. |
Keyword | Alternative splicing; Cell junction; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Keratinization; Nucleus; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 779 AA |
Protein Sequence | MMEDNKQLAL RIDGAVQSAS QEVTNLRAEL TATNRRLAEL SGGGGGPGSG PGAATSASAA 60
AVTVADSAVA TMENHQHGAQ VLLREEVVQL QEEVHLLRQM KEMLAKDLEE SQGGKCSEVL 120
SATELRVQLV QKEQELARAK EALQAMKADR KRLKGEKTDL VSQMQQLYAT LESREEQLRD 180
FIRNYEQHRK ESEDAVKALA KEKDLLEREK WELRRQAKEA TDHAAALRSQ LDLKDNRMKE 240
LEAELAMAKQ SLATLTKDVP KRHSLAMPGE TVLNGNQEWV VQADLPLTAA IRQSQQTLYH 300
SHPPHPADRQ VRVSPCHSRQ PSVISDASAA EGDRSSTPSD INSPRHRTHS LCNGDSPGPV 360
QKSLHNPIVQ SLEDLEDQKR KKKKEKMGFG SISRVFARGK QRKSLDPGLF DDSDSQCSPT 420
RHSLSLSEGE EQMDRLQHVE LVRTTPMSHW KAGTVQAWLE VVMAMPMYVK ACAENVKSGK 480
VLLSLSDEDL ELGLGVCSSL HRRKLRLAIE DYRDAEAGRS LSKAADLDHH WVAKAWLNDI 540
GLSQYSQAFQ NHLVDGRMLN SLMKRDLEKH LNVSKKFHQV SILLGIELLY QVNFSREALQ 600
ERRARCETQN TDPVVWTNQR VLKWVRDIDL KEYADNLTNS GVHGAVLVLE PTFNAEAMAT 660
ALGIPSGKHI LRRHLAEEMS TIFHPSNSTG IRESERFGTP PGRASSITRA GREDSGGNSK 720
HRAGRLPLGK IGRGFSSKEP DFHDDYGSLE NEDCGDEDLQ GRPEQCRLEG YGSLEVTNV 779 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |