UniProt Accession

 EI3G1_DROME; Q9W4X7 

Genbank Protein ID

 AE014298; AY118933 

Genbank Nucleotide ID

 AAF45796.1; AAM50793.1 

Protein Name

 Eukaryotic translation initiation factor 3 subunit G-1 

Protein Synonyms/Alias

 eIF3g-1; Eukaryotic translation initiation factor 3 RNA-binding subunit 1; eIF-3 RNA-binding subunit 1; Eukaryotic translation initiation factor 3 subunit 4-1 

Gene Name

 eIF3-S4-1 

Gene Synonyms/Alias

 CG8636 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
165	VDAPKSGKYVPPFLK	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. This subunit can bind 18S rRNA (By similarity). 

Sequence Annotation

 DOMAIN 188 266 RRM.
 MOD_RES 198 198 Phosphoserine.  

Keyword

 Complete proteome; Cytoplasm; Initiation factor; Phosphoprotein; Protein biosynthesis; Reference proteome; RNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 269 AA 

Protein Sequence

Gene Ontology

 GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:HAMAP.
 GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:HAMAP.
 GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:FlyBase.
 GO:0003729; F:mRNA binding; ISS:FlyBase.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003743; F:translation initiation factor activity; ISS:FlyBase.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0001731; P:formation of translation preinitiation complex; IEA:HAMAP.
 GO:0007067; P:mitosis; IMP:FlyBase.
 GO:0000022; P:mitotic spindle elongation; IMP:FlyBase.
 GO:0051726; P:regulation of cell cycle; IDA:FlyBase.
 GO:0006446; P:regulation of translational initiation; IEA:HAMAP. 

Interpro

 IPR017334; eIF3_g.
 IPR024675; eIF3g_N.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom.
 IPR001878; Znf_CCHC. 

Pfam

 PF12353; eIF3g
 PF00076; RRM_1 

SMART

 SM00360; RRM
 SM00343; ZnF_C2HC 

PROSITE

 PS50102; RRM 

PRINTS