| Tag | Content |
|---|
| CPLM ID | CPLM-026647 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Carbamoyl-phosphate synthase large chain |
Protein Synonyms/Alias | Carbamoyl-phosphate synthetase ammonia chain |
Gene Name | carB |
Gene Synonyms/Alias | RPA4071 |
Created Date | July 27, 2013 |
Organism | Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) |
NCBI Taxa ID | 258594 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 909 | ARIMAGEKIADLGLK | acetylation | [1] |
|
Reference | [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases. Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC. J Biol Chem. 2012 May 4;287(19):15590-601. [ PMID: 22416131] |
Functional Description | |
Sequence Annotation | DOMAIN 138 333 ATP-grasp 1 (By similarity).
DOMAIN 694 906 ATP-grasp 2 (By similarity).
NP_BIND 164 221 ATP (By similarity).
NP_BIND 720 798 ATP (By similarity).
REGION 1 408 Carboxyphosphate synthetic domain (By
REGION 409 565 Oligomerization domain (By similarity).
REGION 566 971 Carbamoyl phosphate synthetic domain (By
REGION 972 1109 Allosteric domain (By similarity).
METAL 290 290 Magnesium or manganese 1 (By similarity).
METAL 304 304 Magnesium or manganese 1 (By similarity).
METAL 304 304 Magnesium or manganese 2 (By similarity).
METAL 306 306 Magnesium or manganese 2 (By similarity).
METAL 865 865 Magnesium or manganese 3 (By similarity).
METAL 877 877 Magnesium or manganese 3 (By similarity).
METAL 877 877 Magnesium or manganese 4 (By similarity).
METAL 879 879 Magnesium or manganese 4 (By similarity). |
Keyword | Amino-acid biosynthesis; Arginine biosynthesis; ATP-binding; Complete proteome; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Pyrimidine biosynthesis; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1109 AA |
Protein Sequence | MPKRTDISTI LIIGAGPIVI GQACEFDYSG TQAVKALKQE GYRVVLVNSN PATIMTDPEL 60
ADATYIEPIT PEIVAKIIEK ERYVIPGGFA LLPTMGGQTA LNCALSLRKL GTLEKFDVEM 120
IGATADAIDK AEDRERFREA MTKIGLETPN SRQVKSLPDA LRALDEIGFP ALIRPSFTMG 180
GTGGGIAYTK AEFIEIVERG IDASPTNEVL IEESILGWKE YEMEVVRDKH DNCIIVCSIE 240
NLDPMGVHTG DSITVAPALT LTDKEYQIMR DASLAVLREI GVETGGSNVQ FAVNPDDGRL 300
VVIEMNPRVS RSSALASKAT GFPIAKVAAK LAVGYSLDEI ANDITGGATP ASFEPTIDYV 360
VTKIPRFAFE KFPGASPTLT TAMKSVGEVM AIGRTFQESL QKALRGLESG LTGLDEIEID 420
GLGRGDDKNA IRAALGTPTP SRLLQVAQAM RLGWSNEEIF NSCKIDPWFL AQLRGIVDME 480
ARVREAGLPD HAFGMRTLKA MGFSDARLAV LADTTEAEVK AKRRALGVRP VFKRIDTCAA 540
EFASPTAYMY STYESPFAGP ASDESRPSDK QKVIILGGGP NRIGQGIEFD YCCCHACFAL 600
HDAGYESIMV NCNPETVSTD YDTADRLYFE PLTGEDVLEI IDTERSNGTL RGVIVQFGGQ 660
TPLKLARALE AADVPILGTS PDAIDLAEDR DRFKRILDKL RLKQPKNGIA YSVEQARLVA 720
AELGLPLVVR PSYVLGGRAM QIIREDNQLS DYLLGTLPEL VPGDVKARYP NDKTGQINTV 780
LGTNPLLFDR YLSDATEVDV DCLSDGKDTF IVGIMEHIEE AGIHSGDSAC SLPPHSLSAE 840
TIAELERQTR ELALGLDVVG LMNVQYAIKD GEIYVLEVNP RASRTVPFVA KVIGMPVAKL 900
AARIMAGEKI ADLGLKKRNL DHVGVKESVF PFARFPGVDT VLGPEMRSTG EVMGIDRSFE 960
IAFAKSQLGG GTRVPRKGTV FVSVRESDKA RIVDAVKLLH SVGFKVIATS GTQRYLSDHG 1020
VPAEKVNKVL EGRPHIVDAI MNGEVQLVFN TTEGPQALAD SRSLRRAALL HKVPYYTTLS 1080
GAVAAAKGIR AYLDGDLEVR TLQSYFSES 1109 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:HAMAP. GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:HAMAP. GO:0000287; F:magnesium ion binding; IEA:HAMAP. GO:0030145; F:manganese ion binding; IEA:HAMAP. GO:0044205; P:'de novo' UMP biosynthetic process; IEA:UniProtKB-UniPathway. GO:0006526; P:arginine biosynthetic process; IEA:HAMAP. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |