CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041847
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCG55033 
Protein Synonyms/Alias
 Uncharacterized protein 
Gene Name
 Gm10250 
Gene Synonyms/Alias
 mCG_55033 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
144NEIFPETKLDKKYPYacetylation[1, 2, 3]
144NEIFPETKLDKKYPYsuccinylation[2]
147FPETKLDKKYPYWPHacetylation[4, 5]
148PETKLDKKYPYWPHQacetylation[1, 2, 4]
148PETKLDKKYPYWPHQsuccinylation[2]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [4] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379]
 [5] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 160 AA 
Protein Sequence
MAGRKLALKT IDWVSFVEVM PQNQKAIGNA LKSWNETFHA RLASLSEKPP AIDWAYYRAN 60
VAKPGLVDDF EKKYNALKIP VPEDKYTALV DQEEKEDVKS CAEFVSGSQL RIQEYEKQLE 120
KMRNIIPFDQ MTIDDLNEIF PETKLDKKYP YWPHQPIENL 160 
Gene Ontology
 GO:0000276; C:mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); IEA:InterPro.
 GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
 GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro. 
Interpro
 IPR008689; ATPase_F0-cplx_dsu_mt. 
Pfam
 PF05873; Mt_ATP-synt_D 
SMART
  
PROSITE
  
PRINTS