CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027193
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Calcium/calmodulin-dependent protein kinase IV 
Protein Synonyms/Alias
 Calcium/calmodulin-dependent protein kinase IV, isoform CRA_a; Calcium/calmodulin-dependent protein kinase type IV 
Gene Name
 Camk4 
Gene Synonyms/Alias
 mCG_140514 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
71TQKPYALKVLKKTVDubiquitination[1]
129LFDRIVEKGYYSERDubiquitination[1]
178PAPDAPLKIADFGLSubiquitination[1]
186IADFGLSKIVEHQVLubiquitination[1]
327RKLKAAVKAVVASSRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 469 AA 
Protein Sequence
MLKVTVPSCP SSPCSSVTAS TENLVPDYWI DGSNRDPLGD FFEVESELGR GATSIVYRCK 60
QKGTQKPYAL KVLKKTVDKK IVRTEIGVLL RLSHPNIIKL KEIFETPTEI SLVLELVTGG 120
ELFDRIVEKG YYSERDAADA VKQILEAVAY LHENGIVHRD LKPENLLYAT PAPDAPLKIA 180
DFGLSKIVEH QVLMKTVCGT PGYCAPEILR GCAYGPEVDM WSVGIITYIL LCGFEPFYDE 240
RGDQFMFRRI LNCEYYFISP WWDEVSLNAK DLVKKLIVLD PKKRLTTFQA LQHPWVTGKA 300
ANFVHMDTAQ KKLQEFNARR KLKAAVKAVV ASSRLGSASS SHTSIQENHK ASSDPPSTQD 360
AKDSTDLLGK KMQEEDQEED QVEAEASADE MRKLQSEEVE KDAGVKEEET SSMVPQDPED 420
ELETDDPEMK RDSEEKLKSV EEEMDPMTEE EAPDAGLGVP QQDAIQPEY 469 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:MGI.
 GO:0007616; P:long-term memory; IEA:Compara.
 GO:0043011; P:myeloid dendritic cell differentiation; IEA:Compara.
 GO:0007270; P:neuron-neuron synaptic transmission; IMP:MGI.
 GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.
 GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:MGI.
 GO:0007165; P:signal transduction; IDA:MGI. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00069; Pkinase 
SMART
 SM00220; S_TKc 
PROSITE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS