UniProt Accession

 AIF1L_MOUSE; Q9EQX4; Q8C150 

Genbank Protein ID

 AB035322; AB094629; AK028955; AK045539; BC024599 

Genbank Nucleotide ID

 BAB20749.1; BAC55012.1; BAC26211.1; BAC32410.1; AAH24599.1 

Protein Name

 Allograft inflammatory factor 1-like 

Protein Synonyms/Alias

 Ionized calcium-binding adapter molecule 2 

Gene Name

 Aif1l 

Gene Synonyms/Alias

 Iba2 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
13	SNRFQGGKAFGLLKA	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for function (By similarity). 

Sequence Annotation

 DOMAIN 47 82 EF-hand 1.
 DOMAIN 83 117 EF-hand 2; degenerate.
 MOD_RES 2 2 N-acetylserine (By similarity).
 MOD_RES 2 2 Phosphoserine (By similarity).  

Keyword

 Acetylation; Actin-binding; Calcium; Cell membrane; Cell projection; Complete proteome; Cytoplasm; Cytoskeleton; Membrane; Metal-binding; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 150 AA 

Protein Sequence

Gene Ontology

 GO:0005884; C:actin filament; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005925; C:focal adhesion; IEA:Compara.
 GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
 GO:0051015; F:actin filament binding; ISS:UniProtKB.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR002048; EF_hand_dom. 

Pfam

  

SMART

  

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 

PRINTS