CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013665
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized protein C3orf38 
Protein Synonyms/Alias
  
Gene Name
 C3orf38 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
101HAKDYWQKQPQLKLKubiquitination[1]
108KQPQLKLKETPEPVTubiquitination[1]
116ETPEPVTKTEDIHLFubiquitination[2]
128HLFQQQVKEDKKAEKubiquitination[3, 4]
318NEVRHNVKQASDSGTubiquitination[1, 2, 3, 4, 5]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [5] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
 May be involved in apoptosis regulation. 
Sequence Annotation
  
Keyword
 Alternative splicing; Apoptosis; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 329 AA 
Protein Sequence
MEMSGLSFSE MEGCRNLLGL LDNDEIMALC DTVTNRLVQP QDRQDAVHAI LAYSQSAEEL 60
LRRRKVHREV IFKYLATQGI VIPPATEKHN LIQHAKDYWQ KQPQLKLKET PEPVTKTEDI 120
HLFQQQVKED KKAEKVDFRR LGEEFCHWFF GLLNSQNPFL GPPQDEWGPQ HFWHDVKLRF 180
YYNTSEQNVM DYHGAEIVSL RLLSLVKEEF LFLSPNLDSH GLKCASSPHG LVMVGVAGTV 240
HRGNTCLGIF EQIFGLIRCP FVENTWKIKF INLKIMGESS LAPGTLPKPS VKFEQSDLEA 300
FYNVITVCGT NEVRHNVKQA SDSGTGDQV 329 
Gene Ontology
 GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. 
Interpro
 IPR026698; UPF_C3orf38. 
Pfam
  
SMART
  
PROSITE
  
PRINTS