CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040768
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Myb-related protein B 
Protein Synonyms/Alias
  
Gene Name
 MYBL2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
387GTPPSVLKRQRKRRVubiquitination[1]
509LEKYGPLKPLPQTPHacetylation[2]
509LEKYGPLKPLPQTPHubiquitination[1, 2]
615NQGFLQAKPEKAAVAacetylation[3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 676 AA 
Protein Sequence
MSRRTRCEDL DELHYQDTDS DVPEQRDSKC KVKWTHEENR TDQQCQYRWL RVLNPDLVKG 60
PWTKEEDQKV IELVKKYGTK QWTLIAKHLK GRLGKQCRER WHNHLNPEVK KSCWTEEEDR 120
IICEAHKVLG NRWAEIAKML PGRTDNAVKN HWNSTIKRKV DTGGFLSESK DCKPPVYLLL 180
ELEDKDGLQS AQPTEGQGSL LTNWPSVPPT IKEEENSEEE LAAATTSKEQ EPIGTDLDAV 240
RTPEPLEEFP KREDQEGSPP ETSLPYKWVV EAANLLIPAV GSSLSEALDL IESDPDAWCD 300
LSKFDLPEEP SAEDSINNSL VQLQASHQQQ VLPPRQPSAL VPSVTEYRLD GHTISDLSRS 360
SRGELIPISP STEVGGSGIG TPPSVLKRQR KRRVALSPVT ENSTSLSFLD SCNSLTPKST 420
PVKTLPFSPS QFLNFWNKQD TLELESPSLT STPVCSQKVV VTTPLHRDKT PLHQKHAAFV 480
TPDQKYSMDN TPHTPTPFKN ALEKYGPLKP LPQTPHLEED LKEVLRSEAG IELIIEDDIR 540
PEKQKRKPGL RRSPIKKVRK SLALDIVDED VKLMMSTLPK SLSLPTTAPS NSSSLTLSGI 600
KEDNSLLNQG FLQAKPEKAA VAQKPRSHFT TPAPMSSAWK TVACGGTRDQ LFMQEKARQL 660
LGRLKPSHTS RTLILS 676 
Gene Ontology
 GO:0003682; F:chromatin binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro. 
Interpro
 IPR015395; C-myb_C.
 IPR009057; Homeodomain-like.
 IPR017877; Myb-like_dom.
 IPR017930; Myb_dom.
 IPR001005; SANT/Myb. 
Pfam
 PF09316; Cmyb_C 
SMART
 SM00717; SANT 
PROSITE
 PS51294; HTH_MYB
 PS50090; MYB_LIKE 
PRINTS