CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038990
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Microphthalmia-associated transcription factor 
Protein Synonyms/Alias
  
Gene Name
 Mitf 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
45AEHSGASKPPLSSSTacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 526 AA 
Protein Sequence
MQSESGIVAD FEVGEEFHEE PKTYYELKSQ PLKSSSSAEH SGASKPPLSS STMTSRILLR 60
QQLMREQMQE QERREQQQKL QAAQFMQQRV AVSQTPAINV SVPTTLPSAT QVPMEVLKVQ 120
THLENPTKYH IQQAQRHQVK QYLSTTLANK HAGQVLSPPC PNQPGDHAMP PVPGSSAPNS 180
PMAMLTLNSN CEKEAFYKFE EQSRAESECP GMNTHSRASC MQMDDVIDDI ISLESSYNEE 240
ILGLMDPALQ MANTLPVSGN LIDLYSNQGL PPPGLTISNS CPANLPNIKR ELTACIFPTE 300
SEARALAKER QKKDNHNLIE RRRRFNINDR IKELGTLIPK SNDPDMRWNK GTILKASVDY 360
IRKLQREQQR AKDLENRQKK LEHANRHLLL RVQELEMQAR AHGLSLIPST GLCSPDLVNR 420
IIKQEPVLEN CSQELVQHQA DLTCTTTLDL TDGTISFTNN LGTMPESSPA YSIPRKMASN 480
LEDILMDDAL SPVGVTDPLL SSVSPGASKT SSRRSSMSAE ETEHAC 526 
Gene Ontology
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB. 
Interpro
 IPR011598; bHLH_dom.
 IPR024097; bHLH_ZIP_TF.
 IPR021802; bHLH_ZIP_TF_MiT/TFE. 
Pfam
 PF11851; DUF3371
 PF00010; HLH 
SMART
 SM00353; HLH 
PROSITE
 PS50888; BHLH 
PRINTS