CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025547
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ERp60 
Protein Synonyms/Alias
 Erp60; IP10683p 
Gene Name
 ERp60 
Gene Synonyms/Alias
 ERp60-RA; CG8983; Dmel_CG8983 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
58CGHCKRLKPEYAKAAacetylation[1]
69AKAAEIVKDDDPPIKacetylation[1]
79DPPIKLAKVDCTEAGacetylation[1]
124REASGIAKYMRAQVGacetylation[1]
171KLAKIFLKFADKNREacetylation[1]
188RFGHSSEKEVLDKQGacetylation[1]
465REVDDFLKYIAKEATacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Isomerase; Redox-active center; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 489 AA 
Protein Sequence
MMWRLAGVLL LGFIAISSGA EQDVLELGDD DFATTLKQHE TTLVMFYAPW CGHCKRLKPE 60
YAKAAEIVKD DDPPIKLAKV DCTEAGKETC SKYSVSGYPT LKIFRQDEVS QDYNGPREAS 120
GIAKYMRAQV GPASKTVRTV AELKKFLDTK DTTLFGYFSD SDSKLAKIFL KFADKNREKY 180
RFGHSSEKEV LDKQGETDKI VLIRAPHLSN KFESSSIKFE GSSESDLSTF VKENFHGLVG 240
HRTQDSVKDF QNPLITAYYS VDYQKNPKGT NYWRNRVLKV AKEFVGQINF AIASKDDFQH 300
ELNEYGYDFV GDKPVVLARD EKNLKYALKD EFSVENLQDF VEKLLANELE PYIKSEPIPE 360
SNDAPVKVAV AKNFDDLVIN NGKDTLIEFY APWCGHCKKL SPIYEELAEK LQDEDVAIVK 420
MDATANDVPP EFNVRGFPTL FWLPKDAKNK PVSYNGGREV DDFLKYIAKE ATTELKGFDR 480
SGKPKKTEL 489 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0003756; F:protein disulfide isomerase activity; IEA:EC.
 GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
 GO:0045454; P:cell redox homeostasis; IEA:InterPro.
 GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
 GO:0006457; P:protein folding; IEA:GOC. 
Interpro
 IPR005788; Disulphide_isomerase.
 IPR005792; Prot_disulphide_isomerase.
 IPR005746; Thioredoxin.
 IPR012336; Thioredoxin-like_fold.
 IPR017937; Thioredoxin_CS.
 IPR013766; Thioredoxin_domain. 
Pfam
 PF00085; Thioredoxin 
SMART
  
PROSITE
 PS00194; THIOREDOXIN_1
 PS51352; THIOREDOXIN_2 
PRINTS
 PR00421; THIOREDOXIN.