CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036728
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Store-operated calcium entry-associated regulatory factor 
Protein Synonyms/Alias
  
Gene Name
 TMEM66 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
7*MLLRDVKALTLHYDubiquitination[1, 2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 202 AA 
Protein Sequence
MLLRDVKALT LHYDRYTTSR RLDPIPQLKC VGGTAGCDSY TPKVIQCQNK GWDGYDVQWE 60
CKTDLDIAYK FGKTVVSCEG YESSEDQYVL RGSCGLEYNL DYTELGLQKL KESGKQHGFA 120
SFSDYYYKWS SADSCNMSGL ITIVVLLGIA FVVYKLFLSD GQYSPPPYSE YPPFSHRYQR 180
FTNSAGPPPP GFKSEFTGPQ NT 202 
Gene Ontology
  
Interpro
 IPR009567; DUF1183_TMEM66. 
Pfam
 PF06682; DUF1183 
SMART
  
PROSITE
  
PRINTS