UniProt Accession

 PFD3_MOUSE; P61759; O55228; Q15765; Q3U6M9; Q9CPZ0 

Genbank Protein ID

 AK002282; AK008847; AK077923; AK151527; AK153069; AK159284; AK167064; AK169185; U96760 

Genbank Nucleotide ID

 BAB21986.1; BAB25926.1; BAC37066.1; BAE30475.1; BAE31695.1; BAE34961.1; BAE39225.1; BAE40962.1; AAC23908.1 

Protein Name

 Prefoldin subunit 3 

Protein Synonyms/Alias

 Von Hippel-Lindau-binding protein 1; VBP-1; VHL-binding protein 1 

Gene Name

 Vbp1 

Gene Synonyms/Alias

 Pfdn3 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
58	KLDEQYQKYKFMELN	ubiquitination	[1]
69	MELNLAQKKRRLKGQ	ubiquitination	[1]
81	KGQIPEIKQTLEILK	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity). 

Sequence Annotation

 MOD_RES 58 58 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Chaperone; Complete proteome; Cytoplasm; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 196 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; TAS:MGI.
 GO:0005634; C:nucleus; TAS:MGI.
 GO:0016272; C:prefoldin complex; IEA:InterPro.
 GO:0006457; P:protein folding; IEA:InterPro. 

Interpro

 IPR009053; Prefoldin.
 IPR016655; Prefoldin_su-3.
 IPR004127; Prefoldin_subunit. 

Pfam

 PF02996; Prefoldin 

SMART

  

PROSITE

  

PRINTS