CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005707
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Beta-soluble NSF attachment protein 
Protein Synonyms/Alias
 SNAP-beta; Brain protein I47; N-ethylmaleimide-sensitive factor attachment protein beta 
Gene Name
 Napb 
Gene Synonyms/Alias
 Snapb 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
19QLMAEAEKRVKASHSubiquitination[1]
56ANMFKMAKNWSAAGNubiquitination[1]
93VDAGNAYKKADPQEAubiquitination[1]
153EQSADYYKGEESNSSubiquitination[1]
163ESNSSANKCLLKVAAubiquitination[1]
167SANKCLLKVAAYAAQubiquitination[1]
199TMDNPLLKYSAKDYFubiquitination[1]
203PLLKYSAKDYFFKAAacetylation[2]
203PLLKYSAKDYFFKAAubiquitination[1]
227NAKLALEKYEEMFPAubiquitination[1]
246RECKLLKKLLEAHEEubiquitination[1]
264EAYTEAVKEFDSISRubiquitination[1]
285TMLLRIKKSIQGDGEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
 Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. 
Sequence Annotation
  
Keyword
 Complete proteome; Direct protein sequencing; ER-Golgi transport; Membrane; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 298 AA 
Protein Sequence
MDNAGKEREA VQLMAEAEKR VKASHSFLRG LFGGNTRIEE ACEMYTRAAN MFKMAKNWSA 60
AGNAFCQAAK LHMQLQSKHD SATSFVDAGN AYKKADPQEA INCLNAAIDI YTDMGRFTIA 120
AKHHITIAEI YETELVDIEK AIAHYEQSAD YYKGEESNSS ANKCLLKVAA YAAQLEQYQK 180
AIEIYEQVGA NTMDNPLLKY SAKDYFFKAA LCHFIVDELN AKLALEKYEE MFPAFTDSRE 240
CKLLKKLLEA HEEQNSEAYT EAVKEFDSIS RLDQWLTTML LRIKKSIQGD GEGDGDLK 298 
Gene Ontology
 GO:0070044; C:synaptobrevin 2-SNAP-25-syntaxin-1a complex; IDA:MGI.
 GO:0019905; F:syntaxin binding; IDA:MGI.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0010807; P:regulation of synaptic vesicle priming; IGI:MGI.
 GO:0035494; P:SNARE complex disassembly; IGI:MGI.
 GO:0035249; P:synaptic transmission, glutamatergic; IGI:MGI. 
Interpro
 IPR000744; NSF_attach.
 IPR011990; TPR-like_helical. 
Pfam
  
SMART
  
PROSITE
  
PRINTS
 PR00448; NSFATTACHMNT.