CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028504
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein 4.1 
Protein Synonyms/Alias
  
Gene Name
 Epb4.1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
254VYECVVEKHAKGQDLubiquitination[1]
387KLAPNQTKELEEKVMubiquitination[1]
392QTKELEEKVMELHKSubiquitination[1]
398EKVMELHKSYRSMTPubiquitination[1]
417LEFLENAKKLSMYGVubiquitination[1]
418EFLENAKKLSMYGVDubiquitination[1]
604EGPGAPIKKTPKEAVubiquitination[1]
752SDTANAVKSEIPTKDubiquitination[1]
758VKSEIPTKDVPIVHTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 869 AA 
Protein Sequence
MTTEKSLAAE AENSQHQQQK EEGEGATNSG QQETQLEEAS QAAAAEGSDQ GEQKLKASNG 60
DTPTHEDLTK NKERTSESRG LSRLLSSFLK RPKSQVSEEE GREVESEKEK GEGGQKEIEL 120
GNSLDEDIIL KAPIAAPEPE LKTDPSLDLH SLSSIETQPE CIQNKSYVQN FTSEASIMIW 180
IIKPAQEEHR EDPDSETKEG EGIEECSGTE VKEDPESRAE REPEASQKPV RRHRNMHCKV 240
SLLDDTVYEC VVEKHAKGQD LLKRVCEHLN LLEEDYFGLA LWDSATSKTW LDSAKEIKKQ 300
VRGVPWNFTF NVKFYPPDPA QLTEDITRYY LCLQLRQDIV AGRLPCSFAT LALLGSYTIQ 360
SELGDYDPEL HGMDYVSDFK LAPNQTKELE EKVMELHKSY RSMTPAQADL EFLENAKKLS 420
MYGVDLHKAK DLEGVDIILG VCSSGLLVYK DKLRINRFPW PKVLKISYKR SSFFIKIRPG 480
EQEHYESTIG FKLPSYRAAK KLWKVCVEHH TFFRLTSTDT IPKSKFLALG SKFRYSGRTQ 540
AQTRQASALI DRPAPHFERT ASKRASRSLD GAAAAESTDR SPRPTSAPAI AQSQVTEGPG 600
APIKKTPKEA VKVEEKRGEE PAEPAEPEPT EAWKVEKTHT EVTVPTSNGD QTQKKRERLD 660
GENIYIRHSN LMLEDLDKSQ EEIKKHHASI SELKKNFMES VPEPRPSEWD KRLSTHSPFR 720
TLNINGQVPT GDGPPLVKTQ TVTISDTANA VKSEIPTKDV PIVHTETKTI TYEAAQTEDS 780
NGDLDPGVLL TAQTITSETT SSTTTTQITK TVKGGISETR IEKRIVITGD ADIDHDQVLV 840
QAIKEAKEQH PDMSVTKVVV HQETEISEE 869 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; ISS:MGI.
 GO:0030863; C:cortical cytoskeleton; IDA:MGI.
 GO:0019898; C:extrinsic to membrane; IEA:InterPro.
 GO:0016020; C:membrane; IDA:MGI.
 GO:0003779; F:actin binding; ISS:MGI.
 GO:0030507; F:spectrin binding; ISS:MGI.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0030036; P:actin cytoskeleton organization; ISS:MGI.
 GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
 GO:0032092; P:positive regulation of protein binding; IGI:MGI.
 GO:0008360; P:regulation of cell shape; ISS:MGI. 
Interpro
 IPR008379; Band_4.1_C.
 IPR019749; Band_41_domain.
 IPR019750; Band_41_fam.
 IPR021187; Band_41_protein.
 IPR000798; Ez/rad/moesin_like.
 IPR014847; FERM-adjacent.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
 IPR019748; FERM_central.
 IPR019747; FERM_CS.
 IPR000299; FERM_domain.
 IPR018979; FERM_N.
 IPR018980; FERM_PH-like_C.
 IPR011993; PH_like_dom.
 IPR007477; SAB_dom. 
Pfam
 PF05902; 4_1_CTD
 PF08736; FA
 PF09380; FERM_C
 PF00373; FERM_M
 PF09379; FERM_N
 PF04382; SAB 
SMART
 SM00295; B41 
PROSITE
 PS00660; FERM_1
 PS00661; FERM_2
 PS50057; FERM_3 
PRINTS
 PR00935; BAND41.
 PR00661; ERMFAMILY.