CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034547
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Pbrm1 
Protein Synonyms/Alias
  
Gene Name
 Pbrm1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
414PFFHLPSKKKYPDYYacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Bromodomain; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1634 AA 
Protein Sequence
MGSKRRRATS PSSSVSGDFD DGHHSVPTPG PSRKRRRLSS LPTVDPIAVC HELYNTIRDY 60
KDEQGRLLCE LFIRAPKRRN QPDYYEVVSQ PIDLMKIQQK LKMEEYDDIN LLTADFQLLF 120
NNAKAYYKPD SPEYKAACKL WDLYLRTRNE FVQKGEADDE DDDEDGQDNQ GTMADGSSPG 180
YLKEILEQLL EAIVVATNPS GRLISELFQK LPSKVQYPDY YAIIKEPIDL KTIAQRIQNG 240
SYKSIHAMAK DIDLLAKNAK TYNEPGSQVF KDANSIKKIF YMKKAEIEHH EMTKSSLRIR 300
TATNLAAARL TGPSHNKSSL DEERNPTSKC YRNKRAVQGG RLSAITMALQ YGSESEEDAA 360
LAAARYEEGE SEAESITSFM DVSNPFHQLY DTVRSCRNNQ GQLIAEPFFH LPSKKKYPDY 420
YQQIKMPISL QQIRTKLKNQ EYETLDHLEC DLNLMFENAK RYNVPNSAIY KRVLKLQQVM 480
QAKKKELARR DDIEDGDSMI SSATSDTGSA KRKSKKNIRK QRMKILFNVV LEAREPGSGR 540
RLCDLFMVKP SKKDYPDYYK IILEPMDLKI IEHNIRNDKY AGEEGMMEDM KLMFRNARHY 600
NEEGSQVYND AHILEKLLKD KRKELGPLPD DDDMASPKLK LSRKSGVSPK KSKYMTPMQQ 660
KLNEVYEAVK NYTDKRGRRL SAIFLRLPSR SELPDYYLTI KKPMDMEKIR SHMMANKYQD 720
IDSMVEDFVM MFNNACTYNE PESLIYKDAL VLHKVLLETR RDLEGDEDSH VPNVTLLIQE 780
LIHNLFVSVM SHQDDEGRCY SDSLAEIPAV DPNFPSRPPL TFDIIRKNVE SNRYRRLDLF 840
QEHMFEVLER ARRMNRTDSE IYEDAVELQQ FFIRIRDELC KNGEILLSPA LSYTTKHLHN 900
DVEKEKKEKL PKEIEEDKLK REEEKREAEK SEDSSGTTGL SGLHRTYSQD CSFKNSMYHV 960
GDYVYVEPAE ANLQPHIVCI ERLWEDSAGE KWLYGCWFYR PNETFHLATR KFLEKEVFKS 1020
DYYNKVPVSK ILGKCVVMFV KEYFKLCPET FRDEDVFVCE SRYSAKTKSF KKIKLWTMPI 1080
SSVRFVPRDV PLPVVRVASV FANADKGDEE KSTDNSDDNR AEDSFNLEKE KEDVPVEMSN 1140
GEPGCHYFEQ LRYNDMWLKV GDCVFIKSHG LVRPRVGRIE KVWVRDGAAY FYGPIFIHPE 1200
ETEHEPTKMF YKKEVFLSNL EETCPMSCIL GKCAVLSFKD FLSCRPTEIP ENDILLCESR 1260
YNESDKQMKK FKGLKRFSLS AKVVDDEIYY FRKPIIPQKE PSPLLEKKIQ LLEAKFAELE 1320
GGDDDTEEMG EEDSEVIEPP SLPQLQTPLA NELDLMPYTP PQSTPKSAKG SAKKESSKRK 1380
INMSGYILFS SEMRAVIKAQ HPDYSFGELS RLVGTEWRNL ETAKKAEYEG MMGGYPPGLP 1440
PLQGPVDGLV SMGSMQPLHP GGPPPHHLPP GVPGLPGIPP PGVMNQGVTP MVGTPAPGGS 1500
PYGQQVGVLG PPGQQAPPPY PGPHPTGPPV IQQPTTPMFV APPPKTQRLL HSEAYLKYIE 1560
GLSAESNSIS KWDQTLAARR RDVHLSKEQE SRLPSHWLKS KGAHTTMADA LWRLRDLMLR 1620
DTLNIRQAYN LENV 1634 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:InterPro. 
Interpro
 IPR001025; BAH_dom.
 IPR001487; Bromodomain.
 IPR018359; Bromodomain_CS.
 IPR009071; HMG_box_dom. 
Pfam
 PF01426; BAH
 PF00439; Bromodomain
 PF00505; HMG_box 
SMART
 SM00439; BAH
 SM00297; BROMO
 SM00398; HMG 
PROSITE
 PS51038; BAH
 PS00633; BROMODOMAIN_1
 PS50014; BROMODOMAIN_2
 PS50118; HMG_BOX_2 
PRINTS
 PR00503; BROMODOMAIN.