UniProt Accession

 RMD2_MOUSE; Q8BSE0; A9UN02; Q8CIF1 

Genbank Protein ID

 AK034617; AK139382; BC024059; BR000694 

Genbank Nucleotide ID

 BAC28771.1; BAE23985.1; AAH24059.1; FAA00419.1 

Protein Name

 Regulator of microtubule dynamics protein 2 

Protein Synonyms/Alias

 RMD-2; mRMD-2; Protein FAM82A1 

Gene Name

 Rmdn2 

Gene Synonyms/Alias

 Fam82a; Fam82a1 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
41	RTTMNFPKLLSLGKK	ubiquitination	[1]
48	KLLSLGKKFGSLTLP	ubiquitination	[1]
97	KEEIRFLKETIPKLE	ubiquitination	[1]
185	KLDVLLQKADHLRTN	ubiquitination	[1]
207	FELLCDHKEKFSEET	acetylation	[2, 3]
207	FELLCDHKEKFSEET	ubiquitination	[1]
209	LLCDHKEKFSEETEF	ubiquitination	[1]
237	LSTSTQEKKHYANIG	ubiquitination	[1]
245	KHYANIGKTLGERAI	ubiquitination	[1]
395	PVVTKEDKDAHKEVK	acetylation	[2, 3]
399	KEDKDAHKEVKKMIS	acetylation	[3]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 

Functional Description

  

Sequence Annotation

  

Keyword

 Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Membrane; Microtubule; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 410 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. 

Interpro

 IPR011990; TPR-like_helical. 

Pfam

  

SMART

  

PROSITE

  

PRINTS