CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014331
UniProt Accession
Genbank Protein ID
 X80899 
Genbank Nucleotide ID
Protein Name
 Cytochrome c oxidase subunit 7A-related protein, mitochondrial 
Protein Synonyms/Alias
 Cytochrome c oxidase subunit VIIa-related protein; Silica-induced gene 81 protein; SIG-81 
Gene Name
 Cox7a2l 
Gene Synonyms/Alias
 Cox7rp; Silg81 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
64NKVPELQKFFQKADGacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123
Functional Description
 May be a regulatory subunit of cytochrome c oxidase that mediates the higher level of energy production in target cells by estrogen. 
Sequence Annotation
 MOD_RES 68 68 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 111 AA 
Protein Sequence
MYYKFSSFTQ KLAGAWASEA YTPQGLKPVS TEAPPIIFAT PTKLTSSVTA YDYSGKNKVP 60
ELQKFFQKAD GFHLKRGLPD QMLYRTTMAL TLGGTIYCLI ALYMASQPRN K 111 
Gene Ontology
 GO:0005746; C:mitochondrial respiratory chain; IEA:InterPro.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
 GO:0009055; F:electron carrier activity; IEA:InterPro. 
Interpro
 IPR003177; Cyt_c_oxidase_su7a.
 IPR017267; Cyt_c_oxidase_su7a-rel_mt. 
Pfam
 PF02238; COX7a 
SMART
  
PROSITE
  
PRINTS