CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039804
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cell division cycle and apoptosis regulator protein 1 
Protein Synonyms/Alias
  
Gene Name
 CCAR1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
173RYTVQFSKFSLDCPSubiquitination[1]
291QHPARLVKFLVGMKGubiquitination[2]
399ETLSRGYKQQLVEKLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 646 AA 
Protein Sequence
MPFKWNAQRI QTLPNQNQSQ TQPLLKTPPA VLQPIAPQTT FGVQTQPQPQ SLLQAQISAA 60
SITPLLQTQP QPLLQQPQQK AGLLQPPVRI VSQPQPARRL DPPSRFSGRN DRGDQVPNRK 120
DDRSRERERE RRRSRERSPQ RKRSRERSPR RERERSPRRV RRVVPRYTVQ FSKFSLDCPS 180
CDMMELRRRY QNLYIPSDFF DAQFTWVDAF PLSRPFQLGN YCNFYVMHRE VESLEKNMAI 240
LDPPDADHLY SAKVMLMASP SMEDLYHKSC ALAEDPQELR DGFQHPARLV KFLVGMKGKD 300
EAMAIGGHWS PSLDGPDPEK DPSVLIKTAI RCCKALTGID LSVCTQWYRF AEIRYHRPEE 360
THKGRTVPAH VETVVLFFPD VWHCLPTRSE WETLSRGYKQ QLVEKLQGER KEADGEQDEE 420
EKDDGEAKEI STPTHWSKLD PKTMKVNDLR KELESRALSS KGLKSQLIAR LTKQLKVEEQ 480
KEEQKELEKS EKEEDEDDDR KSEDDKEEEE RKRQEEIERQ RRERRYILPD EPAIIVHPNW 540
AAKSGKFDCS IMSLSVLLDY RLEDNKEHSF EVSLFAELFN EMLQRDFGVR IYKSLLSLPE 600
KEDKKEKDKK SKKDERKDKK EERDDETDEP KPKRRKSGDD KDKKED 646 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0006915; P:apoptotic process; IEA:InterPro. 
Interpro
 IPR025224; DBC1/CARP1.
 IPR025954; DBC1/CARP1_inactive_NUDIX_dom.
 IPR003034; SAP_dom. 
Pfam
 PF14443; DBC1
 PF02037; SAP 
SMART
 SM00513; SAP 
PROSITE
 PS50800; SAP 
PRINTS