CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025080
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tapasin 
Protein Synonyms/Alias
  
Gene Name
 Tapbp 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
450IPEVSKEKATAASLTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 466 AA 
Protein Sequence
MKPLLLLVAV ALGLATVVSV VSAGPEAIEC WFVEDAGGGG LSKKPATLLL RHGPRGPPPR 60
PDLDPKLYFK VDDPAGMLLA AFRRYPAGAS APHCEMSRFI PFPASAKWAR SLSPEQNCPR 120
ALDGDWLLVS VSSTLFSLSS LLRPQPEPLR EPVVITMATV VLTVLTHNPA PRVQLGKDAV 180
LDLRFAYAPS ALEGSPSLDA GPPPFGLEWR RQHRGKGHLL LAATPGLAGR MPPAQEKATA 240
FAAWDDDEPW GPWTGNGTFW LPAVKPSQEG VYLATVHLPY LQGQVSLELT VHKAPRVSLT 300
PAPVVWAAPG EAPPELLCLA SHFFPAEGLE VKWELRGGPG GSSRKVEGKT WLSTIRHHSD 360
GSVSQSGHLQ LPPVTAKQHG VHYVCRVYHS SLPASGRSAD VTLEVAGFSG PSIEDGIGLF 420
LSAFLLLGLL KVLGWLVAAY WTIPEVSKEK ATAASLTIPR NSKKSQ 466 
Gene Ontology
 GO:0000139; C:Golgi membrane; IEA:Compara.
 GO:0005887; C:integral to plasma membrane; TAS:MGI.
 GO:0042825; C:TAP complex; IEA:Compara.
 GO:0019885; P:antigen processing and presentation of endogenous peptide antigen via MHC class I; IEA:InterPro.
 GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; IDA:MGI.
 GO:0006952; P:defense response; IMP:MGI. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set.
 IPR003599; Ig_sub.
 IPR008056; Tapasin. 
Pfam
 PF07654; C1-set 
SMART
 SM00409; IG 
PROSITE
 PS50835; IG_LIKE
 PS00290; IG_MHC 
PRINTS
 PR01669; TAPASIN.