UniProt Accession

 E9Q1T1_MOUSE; E9Q1T1 

Genbank Protein ID

 AC102591; AC110174 

Genbank Nucleotide ID

  

Protein Name

 Calcium/calmodulin-dependent protein kinase type II subunit beta 

Protein Synonyms/Alias

  

Gene Name

 Camk2d 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
43	TGQEYAAKIINTKKL	ubiquitination	[1]
48	AAKIINTKKLSARDH	ubiquitination	[1]
138	GVVHRDLKPENLLLA	ubiquitination	[1]
251	EAKDLINKMLTINPA	ubiquitination	[1]
259	MLTINPAKRITASEA	ubiquitination	[1]
268	ITASEALKHPWICQR	ubiquitination	[1]
318	TRNFSAAKSLLKKPD	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 533 AA 

Protein Sequence

Gene Ontology

 GO:0043194; C:axon initial segment; IDA:MGI.
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0014704; C:intercalated disc; IDA:MGI.
 GO:0031594; C:neuromuscular junction; IDA:MGI.
 GO:0043025; C:neuronal cell body; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0030315; C:T-tubule; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:InterPro.
 GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
 GO:0006816; P:calcium ion transport; IDA:MGI.
 GO:0060048; P:cardiac muscle contraction; IDA:MGI.
 GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.
 GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.
 GO:0046777; P:protein autophosphorylation; IMP:MGI.
 GO:0002028; P:regulation of sodium ion transport; IDA:MGI. 

Interpro

 IPR020636; Ca/CaM-dep_Ca-dep_prot_Kinase.
 IPR013543; Ca/CaM-dep_prot_kinase-assoc.
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 

Pfam

 PF08332; CaMKII_AD
 PF00069; Pkinase 

SMART

 SM00220; S_TKc 

PROSITE

 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 

PRINTS