UniProt Accession

 SUPH_ECOLI; P75792 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC73909.1; BAA35503.1 

Protein Name

 Sugar phosphatase YbiV 

Protein Synonyms/Alias

  

Gene Name

 ybiV 

Gene Synonyms/Alias

 supH; b0822; JW0806 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
19	GTFLNDAKTYNQPRF	acetylation	[1]
34	MAQYQELKKRGIKFV	acetylation	[1]
77	ALVYEHGKQLFHGEL	acetylation	[1]
98	IVIGELLKDKQLNFV	acetylation	[1]
137	YHRLKPVKDYQEIDD	acetylation	[1]
224	GNDAEMLKMARYSFA	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-phosphate (Fru1P) most efficiently, but it remains uncertain if this is the real substrate in vivo. Appears to have a low level of phosphotransferase activity using monophosphates as the phosphate donor. 

Sequence Annotation

 REGION 9 11 Substrate (By similarity).
 REGION 44 46 Substrate binding.
 ACT_SITE 9 9 Nucleophile.
 METAL 9 9 Magnesium.
 METAL 11 11 Magnesium.
 METAL 215 215 Magnesium.
 METAL 216 216 Magnesium.
 BINDING 192 192 Substrate.  

Keyword

 3D-structure; Complete proteome; Hydrolase; Magnesium; Metal-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 271 AA 

Protein Sequence

Gene Ontology

 GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
 GO:0050308; F:sugar-phosphatase activity; IDA:EcoCyc. 

Interpro

 IPR023214; HAD-like_dom.
 IPR006379; HAD-SF_hydro_IIB.
 IPR000150; Hypothet_cof. 

Pfam

 PF08282; Hydrolase_3 

SMART

  

PROSITE

 PS01228; COF_1
 PS01229; COF_2 

PRINTS