| Tag | Content |
|---|
| CPLM ID | CPLM-017539 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dynein assembly factor 3, axonemal |
Protein Synonyms/Alias | |
Gene Name | DNAAF3 |
Gene Synonyms/Alias | C19orf51 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 247 | RFWAGGEKGPQAFPM | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia. |
Sequence Annotation | |
Keyword | Alternative splicing; Ciliopathy; Cilium biogenesis/degradation; Complete proteome; Cytoplasm; Disease mutation; Polymorphism; Primary ciliary dyskinesia; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 541 AA |
Protein Sequence | MLPLLDSSKR AGTLGSGCGV PRVHSAALSR EEGASRDIWR IKVWARVMTT PAGSGSGFGS 60
VSWWGLSPAL DLQAERDATV DALPTTMVPQ PAVILPGPPV DPDSQADTVH SNPELDVLLL 120
GSVDGRHLLR TLSRAKFWPR RRFNFFVLEN NLEAVARHML IFSLALEEPE KMGLQERSET 180
FLEVWGNALL RPPVAAFVRA QADLLAHLVP EPDRLEEQLP WLSLRALKFR ERDALEAVFR 240
FWAGGEKGPQ AFPMSRLWDS RLRHYLGSRY DARRGVSDWD LRMKLHDRGA QVIHPQEFRR 300
WRDTGVAFEL RDSSAYHVPN RTLASGRLLS YRGERVAARG YWGDIATGPF VAFGIEADDE 360
SLLRTSNGQP VKTAGEITQH NVTELLRDVA AWGRARATGG DLEEQQHAEG SPEPGTPAPT 420
PESFTVHFLP LDSAQTLHHK SCYNGRFQLL YVACGMVHLL IPELGACVAP GGNLIVELAR 480
YLVDVRQEQL QGFNTRVREL AQAAGFAPQT GARPSETFAR FCKSQESALG NTVPAVEPGT 540
PPLDILAQPL EASNPALEGL TQPLQGGTPH CEPCQLPSES PGSLSEVLAQ PQGALAPPNC 600
ESDSKTGV 608 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB. GO:0044458; P:motile cilium assembly; IMP:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |