| Tag | Content |
|---|
| CPLM ID | CPLM-024562 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 850 |
Protein Synonyms/Alias | |
Gene Name | ZNF850 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 279 | WRIHTGDKPYECKEC | ubiquitination | [1] | | 340 | GEKPYDCKECGKSFA | ubiquitination | [1] | | 1063 | QSVHTGEKPYECKTC | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation (By similarity). |
Sequence Annotation | DOMAIN 7 78 KRAB.
ZN_FING 197 219 C2H2-type 1.
ZN_FING 225 247 C2H2-type 2; degenerate.
ZN_FING 253 275 C2H2-type 3; degenerate.
ZN_FING 281 303 C2H2-type 4.
ZN_FING 309 331 C2H2-type 5.
ZN_FING 337 359 C2H2-type 6.
ZN_FING 365 387 C2H2-type 7.
ZN_FING 393 415 C2H2-type 8.
ZN_FING 421 443 C2H2-type 9.
ZN_FING 449 471 C2H2-type 10.
ZN_FING 477 499 C2H2-type 11.
ZN_FING 505 527 C2H2-type 12.
ZN_FING 533 555 C2H2-type 13.
ZN_FING 561 583 C2H2-type 14.
ZN_FING 589 611 C2H2-type 15.
ZN_FING 617 639 C2H2-type 16.
ZN_FING 645 667 C2H2-type 17.
ZN_FING 673 695 C2H2-type 18.
ZN_FING 701 723 C2H2-type 19.
ZN_FING 729 751 C2H2-type 20; degenerate.
ZN_FING 757 779 C2H2-type 21.
ZN_FING 785 807 C2H2-type 22.
ZN_FING 813 835 C2H2-type 23.
ZN_FING 841 863 C2H2-type 24.
ZN_FING 869 891 C2H2-type 25.
ZN_FING 897 919 C2H2-type 26.
ZN_FING 925 947 C2H2-type 27.
ZN_FING 953 975 C2H2-type 28.
ZN_FING 981 1003 C2H2-type 29.
ZN_FING 1009 1031 C2H2-type 30.
ZN_FING 1037 1059 C2H2-type 31.
ZN_FING 1065 1087 C2H2-type 32. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1090 AA |
Protein Sequence | MNMEGLVMFQ DLSIDFSQEE WECLDAAQKD LYRDVMMENY SSLVSLGLSI PKPDVISLLE 60
QGKEPWMVSR DVLGGWCRDS EFRCKTKDSC LPKEIYEVTS SQWVRMEKCH SLVGSSVRDD 120
WECKGQFQHQ DINQERYLEK AIMTYETTPT FCLQTSLTLH HRIHPGEKLY KSTECMAFKY 180
GSELTQQQET HTGEKLYKCK ECGKAFHHFS YLVKHQRIHT GEKPCACKEY GKAFISGSHL 240
IQHQKMYTDE RPHECQESVK AFRPSAHLIQ HWRIHTGDKP YECKECGKSF TSGSTLNQHQ 300
QIHTGEKPYH CKQCGKSFTV GSTLIRHQQI HTGEKPYDCK ECGKSFASGS ALIRHQRIHT 360
GEKPYDCKEC GKSFTFHSAL IRHQRIHTGE KPYDCKECGK SFTFRSGLIG HQAIHTGEKP 420
YDCKECGKSF TAGSTLIQHQ RIHTGEKPYD CKECGKSFAS GSALLQHQRI HTGEKPYCCK 480
ECGKSFTFRS TRNRHQRIHT GEKPYNCKEC GKSFASGSAL LQHQRIHTGE KPYHCKECGK 540
SFTFRSGLIG HQAVHTGEKP YDCKECGKSF TSRSALIQHQ RIHTGEKPYH CKECGKSFTV 600
GSTLLQHQQI HTGEKPYDCK ECGKAFRLRL RLTQHQQIHT GEKPYQCQEC GKAFVSVSGL 660
TQHHRIHTGE KPYECPDCGK AFRQRTYLNQ HRRIHTGEKP YECKECGKSF TFCSGLIQHQ 720
QNHTDEKPYD GKECGKSFTS HSTLIQHQQI HTGEKPYDCK ECGKSFTSHS TLIQHQQIHT 780
GEKLYDCKEC GKSFTSHSTL IQHQPLHTGE KPYHCKECGK SFTLRSALIQ HRPVHTGEKR 840
YSCKECGKSF TSRSTLIEHQ RIHTGEKPYH CKECGKSFAF RSAIIQHRRI HTGEKPYDCK 900
ECGKAFRRRS KLTQHQRIHT GEKPYRCHEC GKAFVRFSGL TKHHSIHTGE KPYECKTCGK 960
SFRQRTHLTL HQRIHTGDRP YECKECGKSF TCGSELIRHQ RTHTGEKPYD CKECGKAFRC 1020
PSQLSQHKRI HTGEKTYQCP ECGKAFFYAS GLSRHQSVHT GEKPYECKTC GKAFKQLTQL 1080
TRHQRIHDLT 1090 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |