CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023560
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Peroxisomal trans-2-enoyl-CoA reductase 
Protein Synonyms/Alias
 TERP; PX-2,4-DCR1; Peroxisomal 2,4-dienoyl-CoA reductase; RLF98 
Gene Name
 Pecr 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
51NVVIASRKLDRLTAAacetylation[1]
83AIQCNIRKEEEVNNLacetylation[1]
92EEVNNLVKSTLAKYGacetylation[1]
97LVKSTLAKYGKINFLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity (By similarity). 
Sequence Annotation
 NP_BIND 23 47 NADP (By similarity).
 MOTIF 301 303 Microbody targeting signal (By
 ACT_SITE 179 179 Proton acceptor (By similarity).  
Keyword
 Complete proteome; Fatty acid biosynthesis; Fatty acid metabolism; Lipid biosynthesis; Lipid metabolism; NADP; Oxidoreductase; Peroxisome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 303 AA 
Protein Sequence
MGSWKSGQSY LAAGLLQNQV AVVTGGATGI GKAISRELLH LGCNVVIASR KLDRLTAAVD 60
ELRASQPPSS STQVTAIQCN IRKEEEVNNL VKSTLAKYGK INFLVNNAGG QFMAPAEDIT 120
AKGWQAVIET NLTGTFYMCK AVYNSWMKDH GGSIVNIIVL LNNGFPTAAH SGAARAGVYN 180
LTKTMALTWA SSGVRINCVA PGTIYSQTAV DNYGELGQTM FEMAFENIPA KRVGLPEEIS 240
PLVCFLLSPA ASFITGQLIN VDGGQALYTR NFTIPDHDNW PVGAGDSSFI KKVKESLKKQ 300
ARL 303 
Gene Ontology
 GO:0005739; C:mitochondrion; ISS:UniProtKB.
 GO:0005778; C:peroxisomal membrane; ISS:UniProtKB.
 GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; ISS:UniProtKB.
 GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0033306; P:phytol metabolic process; IEA:Compara. 
Interpro
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom. 
Pfam
  
SMART
  
PROSITE
 PS00061; ADH_SHORT 
PRINTS
 PR00081; GDHRDH.