UniProt Accession

 SYS1_YEAST; P41544; D6VWH1 

Genbank Protein ID

 U22326; Z49279; X87611; AY558345; X03449; BK006943 

Genbank Nucleotide ID

 AAA85159.1; CAA89294.1; CAA60918.1; AAS56671.1; CAA27176.1; DAA08787.1 

Protein Name

 Protein SYS1 

Protein Synonyms/Alias

  

Gene Name

 SYS1 

Gene Synonyms/Alias

 YJL004C; J1402; YJR83.17 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
15	LRVPNELKPSQIFKQ	ubiquitination	[1, 2, 3, 4]

Reference

 [1] A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery.
 Hitchcock AL, Auld K, Gygi SP, Silver PA.
 Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12735-40. [PMID: 14557538]
 [2] Computational identification of ubiquitylation sites from protein sequences.
 Tung CW, Ho SY.
 BMC Bioinformatics. 2008 Jul 15;9:310. [PMID: 18625080]
 [3] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269]
 [4] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Necessary for the targeting of ARL3 to the Golgi. Involved in protein trafficking. May serve as a receptor for acetylated ARL3. 

Sequence Annotation

 MOD_RES 192 192 Phosphoserine.
 CROSSLNK 15 15 Glycyl lysine isopeptide (Lys-Gly)  

Keyword

 Complete proteome; Golgi apparatus; Isopeptide bond; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 203 AA 

Protein Sequence

Gene Ontology

 GO:0030173; C:integral to Golgi membrane; IDA:SGD.
 GO:0005802; C:trans-Golgi network; IDA:SGD.
 GO:0006895; P:Golgi to endosome transport; IGI:SGD.
 GO:0043001; P:Golgi to plasma membrane protein transport; IMP:SGD.
 GO:0000042; P:protein targeting to Golgi; IMP:SGD.
 GO:0016050; P:vesicle organization; IPI:SGD. 

Interpro

 IPR019185; Integral_membrane_SYS1-rel. 

Pfam

 PF09801; SYS1 

SMART

  

PROSITE

  

PRINTS