CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020591
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP synthase subunit s, mitochondrial 
Protein Synonyms/Alias
 ATP synthase-coupling factor B; Mitochondrial ATP synthase regulatory component factor B 
Gene Name
 Atp5s 
Gene Synonyms/Alias
 Atpw 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
118VEKITLCKCHYIEDNacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123
Functional Description
 Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway. 
Sequence Annotation
 REPEAT 62 87 LRR 1.
 REPEAT 88 116 LRR 2.
 REPEAT 117 141 LRR 3.
 REPEAT 142 173 LRR 4.
 REGION 1 61 N-terminal domain.
 METAL 59 59 Magnesium; via carbonyl oxygen (By
 METAL 93 93 Magnesium (By similarity).  
Keyword
 ATP synthesis; CF(0); Complete proteome; Hydrogen ion transport; Ion transport; Leucine-rich repeat; Magnesium; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Repeat; Transit peptide; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 200 AA 
Protein Sequence
MMMFGKISRQ LCSLKKIPWS CDSRYFWEWL NTVFNKVDYE RLRDVGPDRA ASEWLLRCGA 60
KVRYCGHQKW LHDYNTLPGS SIDRYKIQAI DATDSCIMDI GLDHMVGLEH VEKITLCKCH 120
YIEDNCLQRL SQLENLRKSL LELEIIACGN VTDNGVIALR HFRNLKYLFL SDLPGVKDKE 180
YLAQVFKTAL PSLELKLNLK 200 
Gene Ontology
 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006754; P:ATP biosynthetic process; IEA:UniProtKB-KW.
 GO:0015992; P:proton transport; IEA:UniProtKB-KW. 
Interpro
 IPR026063; ATP_synthase_s. 
Pfam
  
SMART
  
PROSITE
 PS51450; LRR 
PRINTS