CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041650
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Secretogranin 2, isoform CRA_a 
Protein Synonyms/Alias
 Secretogranin-2 
Gene Name
 Scg2 
Gene Synonyms/Alias
 rCG_23898 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
135PSALKENKPYALNLEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 619 AA 
Protein Sequence
MAESKAYRFG AVLLLIHLIF LVPGTEAASF QRNQLLQKEP DLRLENVQKF PSPEMIRALE 60
YIEKLRQQAH REESSPDYNP YQGISVPLQL KENGEESHLA ESSRDVLSED EWMRIILEAL 120
RQAENEPPSA LKENKPYALN LEKNFPVDTP DDYETQQWPE RKLKHMRFPL MYEENSRENP 180
FKRTNEIVEE QYTPQSLATL ESVFQELGKL TGPSNQKRER VDEEQKLYTD DEDDVYKTNN 240
IAYEDVVGGE DWSPMEEKIE TQTQEEVRDS KENTEKNEQI NEEMKRSGHL GLPDEGNRKE 300
SKDQLSEDAS KVITYLRRLV NAVGSGRSQS GQNGDRAARL LERPLDSQSI YQLIEISRNL 360
QIPPEDLIEM LKAGEKPNGL VEPEQDLELA VDLDDIPEAD IDRPDMFQSK TLSKGGYPKA 420
PGRGMMEALP DGLSVEDILN VLGMENVANQ KSPYFPNQYS RDKALLRLPY GPGKSRANQI 480
PKVAWIPDVE SRQAPYDNLN DKDQELGEYL ARMLVKYPEL MNTNQLKRVP SPGSSEDDLQ 540
EEEQLEQAIK EHLGQGSSQE MEKLAKVSKR IPAGSLKNED TPNRQYLDED MLLKVLEYLN 600
QEQAEQGREH LAKRAMENM 619 
Gene Ontology
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0030141; C:secretory granule; IEA:InterPro.
 GO:0042056; F:chemoattractant activity; IEA:Compara.
 GO:0001525; P:angiogenesis; IEA:Compara.
 GO:0048245; P:eosinophil chemotaxis; IEA:Compara.
 GO:0050930; P:induction of positive chemotaxis; IEA:Compara.
 GO:0000165; P:MAPK cascade; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Compara. 
Interpro
 IPR018054; Chromogranin_CS.
 IPR001990; Granin. 
Pfam
 PF01271; Granin 
SMART
  
PROSITE
 PS00422; GRANINS_1 
PRINTS