| Tag | Content |
|---|
| CPLM ID | CPLM-010159 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | PTS system glucose-specific EIICBA component |
Protein Synonyms/Alias | EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component |
Gene Name | ptsG |
Gene Synonyms/Alias | MPN_207; MP624 |
Created Date | July 27, 2013 |
Organism | Mycoplasma pneumoniae (strain ATCC 29342 / M129) |
NCBI Taxa ID | 272634 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 636 | GGKLITKKEYLASKA | acetylation | [1] | | 740 | MQDIIQGKVNWEALQ | acetylation | [1] | | 748 | VNWEALQKVINTDQL | acetylation | [1] | | 879 | TKQGEYTKEKSESVV | acetylation | [1] | | 891 | SVVEVDLKKLSKKYN | acetylation | [1] | | 914 | KESLENFKLVPIRQR | acetylation | [1] |
|
Reference | [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium. van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC. Mol Syst Biol. 2012 Feb 28;8:571. [ PMID: 22373819] |
Functional Description | The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport (By similarity). |
Sequence Annotation | DOMAIN 1 284 PTS EIIC type-1; first part.
DOMAIN 479 630 PTS EIIC type-1; second part.
DOMAIN 661 743 PTS EIIB type-1.
DOMAIN 794 907 PTS EIIA type-1.
REGION 285 478 Unknown.
ACT_SITE 683 683 Phosphocysteine intermediate; for EIIB
ACT_SITE 847 847 Tele-phosphohistidine intermediate; for |
Keyword | Cell membrane; Complete proteome; Kinase; Membrane; Phosphotransferase system; Reference proteome; Sugar transport; Transferase; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 940 AA |
Protein Sequence | MQIKAQDTGQ QKKSCLLSNI RNKWKNRNRG SFRQWVGKLS NGLMIPIAVL PIAGIFLGVG 60
DAIAGNAGDL TGLRYFGLFI KNGGDVVFAN LPILFAIAIA ITFSQDAGVA GFSAFVFWAA 120
MNGFMSSLIL PFDKAGKIIT DTSTPIAGFK VLYNKSVPVH AIATTLGLRT LSTSVFGGII 180
VGALTSVLYK KFYAIRLPDV IGFFSGTRFV PIICFVVAIP VALILLMIWP AVSIGLNAIG 240
TGLGFLGGKG YGANSLIFGY IERSLIPFGV HHAFYAPLWY TSAGGSLQEI VNQQVWIRPD 300
FHLSDNYVAR VIGWVDPNNS SMYIIPGALN GQNGSSTGNT MSKDLNGALS AYMSKESTAF 360
LTWKDLVDGL TFKGNFDKMA ENGLLDGSNK IWLGLNGSGI LGKKLLLSDG NVYTITFKTF 420
ANTTPIAWSK GAQAVLPLNA SSTIVNNPTA LAAATQSNNN TNNIKLYPVN SFRVAVESLN 480
PAQYSQGKFP FMLFGIPAAG VAMILAAPKD RRKEAASIVG SAAFTSFLTG ITEPFEFTFL 540
FLAPWLFYGV HAVLAAVSFW LMNILGANVG QTFSGSFIDF ILYGALPDGR RWLANSYLVP 600
IIGLFLAAIY FPTFYFLIKH FNLATPGRGG KLITKKEYLA SKAAAKAEGV SGVAENFTQT 660
QIEAGILLQA YGGKENIVEL GACITKLRVT VKNPELVKEE PIKELGAAGV MRTTPTFFVA 720
VFGTRAAVYK SAMQDIIQGK VNWEALQKVI NTDQLAVEPK ETTPPKEVMP VVQDEIVILS 780
PVNGTLKSLN QVPDETFKQK LVGEGVAIVP SDGHFKAPGE AGVKTELAFP GGHAYIFDID 840
GIKVMLHIGI DTVQINAKKQ PGEPLEVFDI KTKQGEYTKE KSESVVEVDL KKLSKKYNPI 900
TPFVVMKESL ENFKLVPIRQ RGEIKVGQPI FKLVYKKSQA 940 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0016301; F:kinase activity; IEA:UniProtKB-KW. GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:EC. GO:0005351; F:sugar:hydrogen symporter activity; IEA:InterPro. GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |