CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042736
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Flap endonuclease GEN homolog 1 
Protein Synonyms/Alias
  
Gene Name
 GEN1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
27SPQLLVTKKLAHCSVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 290 AA 
Protein Sequence
ATKGKIIRFN RWNETSCNSS PQLLVTKKLA HCSVCSHPGS PKDHERNGCR LCKSDKYCEP 60
HDYEYCCPCE WHRTEHDRQL SEVENNIKKK ACCCEGFPFH EVIQEFLLNK DKLVKVIRYQ 120
RPDLLLFQRF TLEKMEWPNH YACEKLLVLL THYDMIERKL GSRNSNQLQP IRIVKTRIRN 180
GVHCFEIEWE KPEHYAMEDK QHGEFALLTI EEESLFEAAY PEIVAVYQKQ KLEIKGKKQK 240
RIKPKENNLP EPDEVMSFQS HMTLKPTCEI FHKQNSKLNS GISPDPTLPQ 290 
Gene Ontology
 GO:0004518; F:nuclease activity; IEA:InterPro.
 GO:0006281; P:DNA repair; IEA:InterPro.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 
Interpro
 IPR006084; XPG/Rad2. 
Pfam
  
SMART
  
PROSITE
  
PRINTS