CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038713
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 N-alpha-acetyltransferase 30 
Protein Synonyms/Alias
  
Gene Name
 Naa30 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
235DIMRLITKDLSEPYSacetylation[1, 2, 3, 4, 5]
Reference
 [1] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [4] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [5] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 366 AA 
Protein Sequence
MAEVPPGPSS LLPPPAPAAP AAAELRCPFP AGAALACCSE DEEDDEEHEG GCGSPAGGEA 60
ATSAKARSCL RCPQLPPEQQ QQQLNGLIGP ELRHLRAAAT LKSKVLSAAE AAAPDGASKV 120
TATKGAEGHP GERPPHSVPN NARTALPGRS EAAAAAAGAA SDPAAARNGL VEGTEQQEEE 180
EMDEQVRLLS SSLTTGCSLR SSQGREAEPG EDRTIRYVRY ESELQMPDIM RLITKDLSEP 240
YSIYTYRYFI HNWPQLCFLV SGWNENRCVG AIVCKLDMHK KMFRRGYIAM LAVDSKYRRN 300
GIGTNLVKKA IYAMVEGDCD EVVLETEITN KSALKLYENL GFVRDKRLFR YYLNGVDALR 360
LKLWLR 366 
Gene Ontology
 GO:0008080; F:N-acetyltransferase activity; IEA:InterPro. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR000182; GNAT_dom. 
Pfam
 PF00583; Acetyltransf_1 
SMART
  
PROSITE
 PS51186; GNAT 
PRINTS