CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025150
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ariadne homolog 2 (Drosophila), isoform CRA_a 
Protein Synonyms/Alias
  
Gene Name
 Arih2 
Gene Synonyms/Alias
 mCG_16506 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
376ERWENHNKSLQLEAQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Metal-binding; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 492 AA 
Protein Sequence
MSVDMNSQGS DSNEEDYDPN CEEEEEEEED PGDIEDYYVG VASDVEQQGA DAFDPEEYQF 60
TCLTYKESEG ALHEHMTSLA SVLKVSHSVA KLILVNFHWQ VSEILDRYRS NSAQLLVEAR 120
VQPNPSKHVP TAHPPHHCAV CMQFVRKENL LSLACQHQFC RSCWEQHCSV LVKDGVGVGI 180
SCMAQDCPLR TPEDFVFPLL PNEELRDKYR RYLFRDYVES HFQLQLCPGA DCPMVIRVQE 240
PRARRVQCNR CSEVFCFKCR QMYHAPTDCA TIRKWLTKCA DDSETANYIS AHTKDCPKCN 300
ICIEKNGGCN HMQCSKCKHD FCWMCLGDWK THGSEYYECS RYKENPDIVN QSQQAQAREA 360
LKKYLFYFER WENHNKSLQL EAQTYERIHE KIQERVMNNL GTWIDWQYLQ NAAKLLAKCR 420
YTLQYTYPYA YYMESGPRKK LFEYQQAQLE AEIENLSWKV ERADSYDRGD LENQMHIAEQ 480
RRRTLLKDFH DT 492 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0048588; P:developmental cell growth; IEA:Compara.
 GO:0071425; P:hematopoietic stem cell proliferation; IEA:Compara.
 GO:0070936; P:protein K48-linked ubiquitination; IEA:Compara.
 GO:0070534; P:protein K63-linked ubiquitination; IEA:Compara.
 GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Compara.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IPI:MGI. 
Interpro
 IPR002867; Znf_C6HC.
 IPR001878; Znf_CCHC.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF01485; IBR 
SMART
 SM00647; IBR
 SM00184; RING
 SM00343; ZnF_C2HC 
PROSITE
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS