UniProt Accession

 SHLB1_MOUSE; Q9JK48; Q6A059; Q8CDS9; Q8VI52; Q9CT31 

Genbank Protein ID

 AF263364; AF272946; AK172959; AK029647; AK011371; BC024362 

Genbank Nucleotide ID

 AAF73438.1; AAL59846.1; BAD32237.1; BAC26545.1; BAB27575.3; AAH24362.1 

Protein Name

 Endophilin-B1 

Protein Synonyms/Alias

 SH3 domain-containing GRB2-like protein B1 

Gene Name

 Sh3glb1 

Gene Synonyms/Alias

 Kiaa0491 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
10	IMDFNVKKLAADAGT	ubiquitination	[1]
61	IWTEKIMKQTEVLLQ	ubiquitination	[1]
82	IEEFVYEKLDRKAPS	ubiquitination	[1]
376	ERGNQKGKVPITYLE	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion. 

Sequence Annotation

 DOMAIN 27 261 BAR.
 DOMAIN 305 365 SH3.
 REGION 1 30 Membrane-binding amphipathic helix (By
 MOD_RES 145 145 Phosphothreonine; by CDK5 (By  

Keyword

 3D-structure; Alternative splicing; Apoptosis; Coiled coil; Complete proteome; Cytoplasm; Golgi apparatus; Lipid-binding; Membrane; Mitochondrion; Mitochondrion outer membrane; Phosphoprotein; Reference proteome; SH3 domain. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 365 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; ISO:MGI.
 GO:0005783; C:endoplasmic reticulum; IC:MGI.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0016020; C:membrane; IDA:MGI.
 GO:0005740; C:mitochondrial envelope; ISO:MGI.
 GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
 GO:0043234; C:protein complex; IDA:MGI.
 GO:0005504; F:fatty acid binding; IDA:MGI.
 GO:0042171; F:lysophosphatidic acid acyltransferase activity; IDA:MGI.
 GO:0051084; P:'de novo' posttranslational protein folding; IDA:MGI.
 GO:0006915; P:apoptotic process; ISO:MGI.
 GO:0006917; P:induction of apoptosis; ISO:MGI.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0006654; P:phosphatidic acid biosynthetic process; IDA:MGI.
 GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; IMP:MGI.
 GO:0032461; P:positive regulation of protein oligomerization; IEA:Compara.
 GO:0051259; P:protein oligomerization; IEA:Compara. 

Interpro

 IPR027267; AH/BAR-dom.
 IPR004148; BAR_dom.
 IPR001452; SH3_domain. 

Pfam

 PF03114; BAR
 PF00018; SH3_1 

SMART

 SM00721; BAR
 SM00326; SH3 

PROSITE

 PS51021; BAR
 PS50002; SH3 

PRINTS