CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040345
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Peripheral plasma membrane protein CASK 
Protein Synonyms/Alias
  
Gene Name
 Cask 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
31QTVEQLQKMLREMRGubiquitination[1]
107QGKLENSKNGTAGLIubiquitination[1]
133CIAMEKTKQEQQASCubiquitination[1]
204IKNTLITKHPDRFAYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 282 AA 
Protein Sequence
XHRQGTLHVG DEIREINGIS VANQTVEQLQ KMLREMRGSI TFKIVPSYRT QSSSCEIYVR 60
AQFEYDPAKD DLIPCKEAGI RFRVGDIIQI ISKDDHNWWQ GKLENSKNGT AGLIPSPELQ 120
EWRVACIAME KTKQEQQASC TWFGKKKKQY KDKYLAKHNA VFDQLDLVTY EEVVKLPAFK 180
RKTLVLLGAH GVGRRHIKNT LITKHPDRFA YPIPHTTRPP KKDEENGKNY YFVSHDQMMQ 240
DISNNEYLEY GSHEDAMYGT KLETIRKIHE QGLIAILDVE PQ 282 
Gene Ontology
 GO:0016323; C:basolateral plasma membrane; IDA:MGI.
 GO:0005829; C:cytosol; IDA:MGI.
 GO:0045202; C:synapse; IDA:MGI.
 GO:0042043; F:neurexin family protein binding; IDA:MGI.
 GO:0070509; P:calcium ion import; IMP:MGI.
 GO:0090280; P:positive regulation of calcium ion import; IDA:MGI.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI. 
Interpro
 IPR008144; Guanylate_kin.
 IPR008145; Guanylate_kin/L-typ_Ca_channel.
 IPR020590; Guanylate_kinase_CS.
 IPR027417; P-loop_NTPase.
 IPR001478; PDZ.
 IPR011511; SH3_2.
 IPR001452; SH3_domain. 
Pfam
 PF00625; Guanylate_kin
 PF00595; PDZ
 PF07653; SH3_2 
SMART
 SM00072; GuKc
 SM00326; SH3 
PROSITE
 PS00856; GUANYLATE_KINASE_1
 PS50052; GUANYLATE_KINASE_2
 PS50106; PDZ
 PS50002; SH3 
PRINTS