CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009023
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 6.8 kDa mitochondrial proteolipid 
Protein Synonyms/Alias
  
Gene Name
 MP68 
Gene Synonyms/Alias
 C14orf2; PRO1574 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
14KNIWIPMKPYYTKVYacetylation[1]
14KNIWIPMKPYYTKVYubiquitination[2, 3]
49DKRSKALKASAPAPGubiquitination[4]
Reference
 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Membrane; Mitochondrion; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 58 AA 
Protein Sequence
MLQSIIKNIW IPMKPYYTKV YQEIWIGMGL MGFIVYKIRA ADKRSKALKA SAPAPGHH 58 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005753; C:mitochondrial proton-transporting ATP synthase complex; ISS:UniProtKB. 
Interpro
 IPR012574; Mit_proteolip. 
Pfam
 PF08039; Mit_proteolip 
SMART
  
PROSITE
  
PRINTS