UniProt Accession

 FABP7_RAT; P55051 

Genbank Protein ID

 U02096 

Genbank Nucleotide ID

 AAA60455.1 

Protein Name

 Fatty acid-binding protein, brain 

Protein Synonyms/Alias

 Brain lipid-binding protein; BLBP; Brain-type fatty acid-binding protein; B-FABP; Fatty acid-binding protein 7 

Gene Name

 Fabp7 

Gene Synonyms/Alias

 Blbp 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
38	RQVGNVTKPTVIISQ	acetylation	[1]
97	DKLIHVQKWDGKETN	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. 

Sequence Annotation

 REGION 127 129 Fatty acid binding (By similarity).  

Keyword

 Complete proteome; Cytoplasm; Direct protein sequencing; Lipid-binding; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 132 AA 

Protein Sequence

Gene Ontology

 GO:0042995; C:cell projection; IEA:Compara.
 GO:0005737; C:cytoplasm; IDA:RGD.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0005634; C:nucleus; IDA:RGD.
 GO:0005504; F:fatty acid binding; TAS:RGD.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0021846; P:cell proliferation in forebrain; IEA:Compara.
 GO:0050673; P:epithelial cell proliferation; IMP:RGD.
 GO:0022008; P:neurogenesis; IEA:Compara.
 GO:0060134; P:prepulse inhibition; IEA:Compara. 

Interpro

 IPR012674; Calycin.
 IPR011038; Calycin-like.
 IPR000463; Fatty_acid-bd.
 IPR000566; Lipocln_cytosolic_FA-bd_dom. 

Pfam

 PF00061; Lipocalin 

SMART

  

PROSITE

 PS00214; FABP 

PRINTS

 PR00178; FATTYACIDBP.