CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017795
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mitochondrial coenzyme A transporter SLC25A42 
Protein Synonyms/Alias
 Solute carrier family 25 member 42 
Gene Name
 Slc25a42 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
66IIFQVSSKRFSAKEAacetylation[1]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 
Functional Description
 Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'- diphosphate (By similarity). 
Sequence Annotation
 REPEAT 31 117 Solcar 1.
 REPEAT 129 214 Solcar 2.
 REPEAT 224 312 Solcar 3.  
Keyword
 Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 318 AA 
Protein Sequence
MGNGVQEGSV RLREDAEAVL AGAVSSKRDH RQVLSSLLSG ALAGALAKTA VAPLDRTKII 60
FQVSSKRFSA KEAFRLLYFT YLNEGFLSLW RGNSATMVRV IPYAAIQFSA HEEYKRILGH 120
YYGFRGEALP PWPRLLAGAL AGTTAASLTY PLDLVRARMA VTPKEMYSNI FHVFIRISRE 180
EGLKTLYFGF TPTVLGVIPY AGLSFFTYES LKSLHREYSG RPQPYPFERM VFGACAGLIG 240
QSASYPLDVV RRRMQTAGVT GHQHGSILST LRSIVREEGA VRGLYKGLSM NWLKGPIAVG 300
ISFTTFDLMQ ILLRRLQS 318 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0043262; F:adenosine-diphosphatase activity; ISS:UniProtKB.
 GO:0015217; F:ADP transmembrane transporter activity; ISS:UniProtKB.
 GO:0080122; F:AMP transmembrane transporter activity; ISS:UniProtKB.
 GO:0005347; F:ATP transmembrane transporter activity; ISS:UniProtKB.
 GO:0015228; F:coenzyme A transmembrane transporter activity; ISS:UniProtKB. 
Interpro
 IPR014762; DNA_mismatch_repair_CS.
 IPR002167; Graves_DC.
 IPR002067; Mit_carrier.
 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 
Pfam
 PF00153; Mito_carr 
SMART
  
PROSITE
 PS50920; SOLCAR 
PRINTS
 PR00928; GRAVESDC.
 PR00926; MITOCARRIER.