UniProt Accession

 H0YHI0_HUMAN; H0YHI0 

Genbank Protein ID

 AL135745; AL139022 

Genbank Nucleotide ID

  

Protein Name

 Protein CHURC1-FNTB 

Protein Synonyms/Alias

  

Gene Name

 CHURC1-FNTB 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
48	LITNKSLKEEDGEEI	ubiquitination	[1]
89	FQAKVEEKIQEVFSS	ubiquitination	[1]
98	QEVFSSYKFNHLVPR	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 472 AA 

Protein Sequence

Gene Ontology

 GO:0005965; C:protein farnesyltransferase complex; IEA:InterPro.
 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0007275; P:multicellular organismal development; IEA:InterPro.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:InterPro.
 GO:0018343; P:protein farnesylation; IEA:InterPro.
 GO:0042127; P:regulation of cell proliferation; IEA:InterPro. 

Interpro

 IPR026872; FTB.
 IPR001330; Prenyltrans.
 IPR008930; Terpenoid_cyclase/PrenylTrfase.
 IPR009508; Transcrpt_activator_Churchill. 

Pfam

 PF06573; Churchill
 PF00432; Prenyltrans 

SMART

  

PROSITE

  

PRINTS