UniProt Accession

 SNR48_HUMAN; Q6IEG0; A8K8P4; Q14C91; Q5T339; Q5THM1; Q5THM2; Q96MK1 

Genbank Protein ID

 AK056796; AK292409; AL832462; AL031058; AL390026; CH471087; BC114630; BC114631; BK005199 

Genbank Nucleotide ID

 BAB71287.1; BAF85098.1; CAI21647.2; CAI20238.1; EAW55216.1; AAI14631.1; AAI14632.1; DAA05497.1 

Protein Name

 U11/U12 small nuclear ribonucleoprotein 48 kDa protein 

Protein Synonyms/Alias

 U11/U12 snRNP 48 kDa protein; U11/U12-48K 

Gene Name

 SNRNP48 

Gene Synonyms/Alias

 C6orf151 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
73	MPKSSLAKHMASCRL	ubiquitination	[1]
104	EFFYENVKIPSITLN	ubiquitination	[2]
112	IPSITLNKDSQFQII	ubiquitination	[3]
120	DSQFQIIKQARTAVG	ubiquitination	[1]
128	QARTAVGKDSDCYNQ	ubiquitination	[1, 3]
150	VEVPLNHKRFVCDLT	ubiquitination	[2]
173	DFVVEETKKKRSDSQ	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

 Likely involved in U12-type 5' splice site recognition. 

Sequence Annotation

 ZN_FING 58 78 CHHC-type.  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Metal-binding; mRNA processing; mRNA splicing; Nucleus; Polymorphism; Reference proteome; Spliceosome; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 339 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005689; C:U12-type spliceosomal complex; IDA:HGNC.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
 GO:0008380; P:RNA splicing; IC:HGNC. 

Interpro

 IPR022776; TRM13/UPF0224_CHHC_Znf_dom.
 IPR007917; UPF0224. 

Pfam

 PF05253; zf-U11-48K 

SMART

  

PROSITE

  

PRINTS