CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036829
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Electroneutral sodium bicarbonate exchanger 1 
Protein Synonyms/Alias
  
Gene Name
 SLC4A8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
407GGLVLDIKRKAPWYWubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 747 AA 
Protein Sequence
MPLGRQSHRH HRTHGQKHRR RGRGKGASQG EEGLEALAHD TPSQRVQFIL GTEEDEEHVP 60
HELFTELDEI CMKEGEDAEW KETARWLKFE EDVEDGGERW SKPYVATLSL HSLFELRSCL 120
INGTVLLDMH ANSIEEISDL ILDQQELSSD LNDSMRVKVR EALLKKHHHQ NEKKRNNLIP 180
IVRSFAEVGK KQSDPHLMDK HGQTVSPQSV PTTNLEVKNG VNCEHSPVDL SKVDLHFMKK 240
IPTGAEASNV LVGEVDILDR PIVAFVRLSP AVLLSGLTEV PIPTRFLFIL LGPVGKGQQY 300
HEIGRSMATI MTDEIFHDVA YKAKERDDLL AGIDEFLDQV TVLPPGEWDP SIRIEPPKNV 360
PSQEKRKMPG VPNGNVCHIE QEPHGGHSGP ELQRTGRLFG GLVLDIKRKA PWYWSDYRDA 420
LSLQCLASFL FLYCACMSPV ITFGGLLGEA TEGRISAIES LFGASMTGIA YSLFAGQALT 480
ILGSTGPVLV FEKILFKFCK DYALSYLSLR ACIGLWTAFL CIVLVATDAS SLVCYITRFT 540
EEAFASLICI IFIYEAIEKL IHLAETYPIH MHSQLDHLSL YYCRCTLPEN PNNHTLQYWK 600
DHNIVTAEVH WANLTVSECQ EMHGEFMGSA CGHHGPYTPD VLFWSCILFF TTFILSSTLK 660
TFKTSRYFPT RMESCSVAWL ECGGVILAHC NLRLLPSSWD YRHAPPQPAN FCIFSRDGVS 720
PCWPGWSQSL DLVICLPRPP KMLGLQA 747 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro. 
Interpro
 IPR013769; Band3_cytoplasmic_dom.
 IPR011531; HCO3_transpt_C.
 IPR003020; HCO3_transpt_euk.
 IPR003024; Na/HCO3_transpt.
 IPR016152; PTrfase/Anion_transptr. 
Pfam
 PF07565; Band_3_cyto
 PF00955; HCO3_cotransp 
SMART
  
PROSITE
  
PRINTS
 PR01231; HCO3TRNSPORT.
 PR01232; NAHCO3TRSPRT.