CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028044
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 LD47396p 
Protein Synonyms/Alias
 Tcp-1eta 
Gene Name
 Tcp-1eta 
Gene Synonyms/Alias
 CG8351; Dmel_CG8351 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
122VHPRVIIKAIRKALQacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Complete proteome; Cytoplasm; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 544 AA 
Protein Sequence
MQPQIVLLKE GTDSSQGKPQ LVSNINACQS IVDAVRTTLG PRGMDKLIVD AHGKATISND 60
GATIMKLLEI IHPAAKTLVD IAKSQDAEVG DGTTSVVLLA GEFLKQVKPF VEEGVHPRVI 120
IKAIRKALQL CMEKINEMAV QIVEQSKDQQ RALLEKCAAT AMSSKLIHQQ KDFFSRIVVD 180
AVLSLDELLP LNMIGIKKVT GGSLEESQLV SGVAFKKTFS YAGFEMAPKS YDNCKIALLN 240
IELELKAERD NAEIRVDNVK EYQKVVDAEW QILYNKLAKI HESGANVVLS KLPIGDVATQ 300
YFADRDIFCA GRVPEEDLKR TMKACGGAVM TTANDIKPNV LGLCEHFEER QVGGERFNLF 360
QGCPNAKTST LILRGGAEQF LEETERSLHD AIMIVRRTIK HDSVVAGGGA IEMELSKLLR 420
DYSRTIAGKE QLLIAAIAKG LEIIPRQLCD NAGFDATNIL NKLRQKHAQG GQWYGVDINK 480
EDISDNYEQC VWEPSIIKIN ALTAAAEAAC MILSVDETIK SPKAGEPPMA GGGMGMGRGM 540
GRPM 544 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:EC.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0031122; P:cytoplasmic microtubule organization; IMP:FlyBase.
 GO:0007052; P:mitotic spindle organization; IMP:FlyBase.
 GO:0022008; P:neurogenesis; IMP:FlyBase.
 GO:0006457; P:protein folding; IEA:InterPro. 
Interpro
 IPR012720; Chap_CCT_eta.
 IPR017998; Chaperone_TCP-1.
 IPR002194; Chaperonin_TCP-1_CS.
 IPR002423; Cpn60/TCP-1.
 IPR027409; GroEL-like_apical_dom.
 IPR027413; GROEL-like_equatorial.
 IPR027410; TCP-1-like_intermed. 
Pfam
 PF00118; Cpn60_TCP1 
SMART
  
PROSITE
 PS00750; TCP1_1
 PS00751; TCP1_2
 PS00995; TCP1_3 
PRINTS
 PR00304; TCOMPLEXTCP1.