CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038524
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Utrn 
Protein Synonyms/Alias
  
Gene Name
 Utrn 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
458DDLPSLQKLLQEHKSubiquitination[1]
891HHYQAVRKALEEYQQubiquitination[1]
1334SKQISLEKQLQVLREubiquitination[1]
2682AVTSNWQKQVGKALEubiquitination[1]
2767LDLHPSLKMSRQLDDubiquitination[1]
2889NTTNEVFKQHKLNQNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; Calcium; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 3430 AA 
Protein Sequence
MAKYGDLEAR PDDGQNEFSD IIKSRSDEHN DVQKKTFTKW INARFSKSGK PPISDMFSDL 60
KDGRKLLDLL EGLTGTSLPK ERGSTRVHAL NNVNRVLQVL HQNNVDLVNI GGTDIVDGNP 120
KLTLGLLWSI ILHWQVKDVM KDIMSDLQQT NSEKILLSWV RQTTRPYSQV NVLNFTTSWT 180
DGLAFNAVLH RHKPDLFSWD RVVKMSPIER LEHAFSKAHT YLGIEKLLDP EDVAVHLPDK 240
KSIIMYLTSL FEVLPQQVTI DAIREVETLP RKYKKECEEE EIHIQSAVLA EEGQSPRAET 300
PSTVTEVDMD LDSYQIALEE VLTWLLSAED TFQEQDDISD DVEEVKEQFA THETFMMELT 360
AHQSSVGSVL QAGNQLMTQG TLSEEEEFEI QEQMTLLNAR WEALRVESME RQSRLHDALM 420
ELQKKQLQQL SSWLALTEER IQKMESLPLG DDLPSLQKLL QEHKSLQNDL EAEQVKVNSL 480
THMVVIVDEN SGESATALLE DQLQKLGERW TAVCRWTEER WNRLQEISIL WQELLEEQCL 540
LEAWLTEKEE ALNKVQTSNF KDQKELSVSV RRLAILKEDM EMKRQTLDQL SEIGQDVGQL 600
LSNPKASKKM NSDSEELTQR WDSLVQRLED SSNQVTQAVA KLGMSQIPQK DLLETVHVRE 660
QGMVKKPKQE LPPPPPPKKR QIHVDVEAKK KFDAISTELL NWILKSKTAI QNTEMKEYKK 720
SQETSGMKKK LKGLEKEQKE NLPRLDELNQ TGQTLREQMG KEGLSTEEVN DVLERVSLEW 780
KMISQQLEDL GRKIQLQEDI NAYFKQLDAI EETIKEKEEW LRGTPISESP RQPLPGLKDS 840
CQRELTDLLG LHPRIETLCA SCSALKSQPC VPGFVQQGFD DLRHHYQAVR KALEEYQQQL 900
ENELKSQPGP AYLDTLNTLK KMLSESEKAA QASLNALNDP IAVEQALQEK KALDETLENQ 960
KHTLHKLSEE TKTLEKNMLP DVGKMYKQEF DDVQGRWNKV KTKVSRDLHL LEEITPRLRD 1020
FEADSEVIEK WVSGIKDFLM KEQAAQGDAA ALQSQLDQCA TFANEIETIE SSLKNMREVE 1080
TSLQRCPVTG VKTWVQARLV DYQSQLEKFS KEIAIQKSRL SDSQEKALNL KKDLAEMQEW 1140
MAQAEEDYLE RDFEYKSPEE LESAVEEMKR AKEEVLQKEV RVKILKDSIK LVAAKVPSGG 1200
QELTSEFNEV LESYQLLCNR IRGKCHTLEE VWSCWVELLH YLDLETTWLN TLEERVRSTE 1260
ALPERAEAVH EALESLESVL RHPADNRTQI RELGQTLIDG GILDDIISEK LEAFNSRYEE 1320
LSHLAESKQI SLEKQLQVLR ETDHMLQVLK ESLGELDKQL TTYLTDRIDA FQLPQEAQKI 1380
QAEISAHELT LEELRKNVRS QPPTSPEGRA TRGGSQMDML QRKLREVSTK FQLFQKPANF 1440
EQRMLDCKRV LEGVKAELHV LDVRDVDPDV IQAHLDKCMK LYKTLSEVKL EVETVIKTGR 1500
HIVQKQQTDN PKSMDEQLTS LKVLYNDLGA QVTEGKQDLE RASQLSRKMK KEAAVLSEWL 1560
SATEAELVQK STSEGVIGDL DTEISWAKSI LKDLEKRKVD LNGITESSAA LQHLVLGSES 1620
VLEENLCVLN AGWSRVRTWT EDWCNTLLNH QNQLELFDGH VAHISTWLYQ AEALLDEIEK 1680
KPASKQEEIV KRLLSELDDA SLQVENVREQ AIILVNARGS ASRELVEPKL AELSRNFEKV 1740
SQHIKSARML IGQDPSSYQG LDPAGTVQAA ESFSDLENLE QDIENMLKVV EKHLDPNNDE 1800
KMDEEQAQIE EVLQRGEHLL HEPMEDSKKE KIRLQLLLLH TRYNKIKTIP IQQRKTIPVS 1860
SGITSSALPA DYLVEINKIL LTLDDIELSL NMPELNTTVY KDFSFQEDSL KSIKGQLDRL 1920
GEQIAVVHEK QPDVIVEASG PEAIQIRDML AQLNAKWDRV NRVYSDRRGS FARAVEEWRQ 1980
FHHDLDDLTQ WLSEAEDLLV DTCAPDGSLD LEKARAQQLE LEEGLSSHQP SLIKVNRKGE 2040
DLVQRLRPSE ASFLKEKLAG FNQRWSTLVA EVEALQPRLK GESQQVLGYK RRLDEVTCWL 2100
TKVESAVQKR STPDPEESPQ ELTDLAQETE VQAENIKWLN RAELEMLSDK NLSLREREKL 2160
SESLRNVNTT WTKVCREVPS LLKTRTQDPC SAPQMRMAAH PNVQKVVLVS SASDAPLRGG 2220
LEISVPADLD KTITELADWL VLIDQMLKSN IVTVGDVKEI NKTVSRMKIT KADLEQRHPQ 2280
LDCVFTLAQN LKNKASSSDV RTAITEKLEK LKTQWESTQH GVELRRQQLE DMVVDSLQWD 2340
DHREETEELM RKYEARFYML QQARRDPLSK QVSDNQLLLQ ELGSGDGVIM AFDNVLQKLL 2400
EEYSGDDTRN VEETTEYLKT SWVNLKQSIA DRQSALEAEL QTVQTSRRDL ENFVKWLQEA 2460
ETTANVLADA SQRENALQDS VLARQLRQQM LDIQAEIDAH NDIFKSIDGN RQKMVKALGN 2520
SEEATMLQHR LDDMNQRWND LKAKSASIRA HLEASAEKWN RLLASLEELI KWLNMKDEEL 2580
KKQMPIGGDV PALQLQYDHC KVLRRELKEK EYSVLNAVDQ ARVFLADQPI EAPEEPRRNP 2640
QSKTELTPEE RAQKIAKAMR KQSSEVREKW ENLNAVTSNW QKQVGKALEK LRDLQGAMDD 2700
LDADMKEVEA VRNGWKPVGD LLIDSLQDHI EKTLAFREEI APINLKVKTM NDLSSQLSPL 2760
DLHPSLKMSR QLDDLNMRWK LLQVSVDDRL KQLQEAHRDF GPSSQHFLST SVQLPWQRSI 2820
SHNKVPYYIN HQTQTTCWDH PKMTELFQSL ADLNNVRFSA YRTAIKIRRL QKALCLDLLE 2880
LNTTNEVFKQ HKLNQNDQLL SVPDVINCLT TTYDGLEQLH KDLVNVPLCV DMCLNWLLNV 2940
YDTGRTGKIR VQSLKIGLMS LSKGLLEEKY RCLFKEVAGP TEMCDQRQLG LLLHDAIQIP 3000
RQLGEVAAFG GSNIEPSVRS CFQQNNNKPE ISVKEFIDWM HLEPQSMVWL PVLHRVAAAE 3060
TAKHQAKCNI CKECPIVGFR YRSLKHFNYD VCQSCFFSGR TAKGHKLHYP MVEYCIPTTS 3120
GEDVRDFTKV LKNKFRSKKY FAKHPRLGYL PVQTVLEGDN LETPITLISM WPEHYDPSQS 3180
PQLFHDDTHS RIEQYATRLA QMERTNGSFL TDSSSTTGSV EDEHALIQQY CQTLGGESPV 3240
SQPQSPAQIL KSVEREERGE LERIIADLEE EQRNLQVEYE QLKEQHLRRG LPVGSPPDSI 3300
VSPHHTSEDS ELIAEAKLLR QHKGRLEARM QILEDHNKQL ESQLHRLRQL LEQPDSDSRI 3360
NGVSPWASPQ HSALSYSLDT DPGPQFHQAA SEDLLAPPHD TSTDLTDVME QINSTFPSCS 3420
SNVPSRPQAM 3430 
Gene Ontology
 GO:0070938; C:contractile ring; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0016010; C:dystrophin-associated glycoprotein complex; IDA:MGI.
 GO:0030175; C:filopodium; IEA:Compara.
 GO:0031594; C:neuromuscular junction; IDA:MGI.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0007527; P:adult somatic muscle development; TAS:MGI.
 GO:0001954; P:positive regulation of cell-matrix adhesion; IEA:Compara. 
Interpro
 IPR001589; Actinin_actin-bd_CS.
 IPR001715; CH-domain.
 IPR016344; Dystrophin/utrophin.
 IPR011992; EF-hand-like_dom.
 IPR015153; EF-hand_dom_typ1.
 IPR015154; EF-hand_dom_typ2.
 IPR018159; Spectrin/alpha-actinin.
 IPR002017; Spectrin_repeat.
 IPR001202; WW_dom.
 IPR000433; Znf_ZZ. 
Pfam
 PF00307; CH
 PF09068; efhand_1
 PF09069; efhand_2
 PF00435; Spectrin
 PF00397; WW
 PF00569; ZZ 
SMART
 SM00033; CH
 SM00150; SPEC
 SM00456; WW
 SM00291; ZnF_ZZ 
PROSITE
 PS00019; ACTININ_1
 PS00020; ACTININ_2
 PS50021; CH
 PS01159; WW_DOMAIN_1
 PS50020; WW_DOMAIN_2
 PS01357; ZF_ZZ_1
 PS50135; ZF_ZZ_2 
PRINTS