CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038760
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 LIM and senescent cell antigen-like-containing domain protein 1 
Protein Synonyms/Alias
  
Gene Name
 Lims1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
359KFVEFDMKPVCKKCYacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; LIM domain; Metal-binding; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 387 AA 
Protein Sequence
MAFPGRARPC TIPENEEIPQ TALNSVLEAN GNEDERAVSN LQRRHSDVKV YKEFCDFYAK 60
FNMANALASA TCERCKGGFA PAEKIVNSNG ELYHEQCFVC AQCFQQFPEG LFYEFEGRKY 120
CEHDFQMLFA PCCHQCGEFI IGRVIKAMNN SWHPECFRCD LCQEVLADIG FVKNAGRHLC 180
RPCHNREKAR GLGKYICQKC HAIIDEQPLI FKNDPYHPDH FNCANCGKEL TADARELKGE 240
LYCLPCHDKM GVPICGACRR PIEGRVVNAM GKQWHVEHFV CAKCEKPFLG HRHYERKGLA 300
YCETHYNQLF GDVCFHCNRV IEGDVVSALN KAWCVSCFAC STCNTKLTLK NKFVEFDMKP 360
VCKKCYEKFP LELKKRLKKL SETLGRK 387 
Gene Ontology
 GO:0005925; C:focal adhesion; IDA:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0016337; P:cell-cell adhesion; IMP:MGI.
 GO:0045216; P:cell-cell junction organization; IGI:MGI.
 GO:0007160; P:cell-matrix adhesion; IMP:MGI.
 GO:0043009; P:chordate embryonic development; IMP:MGI.
 GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI.
 GO:2001046; P:positive regulation of integrin-mediated signaling pathway; IGI:MGI. 
Interpro
 IPR017351; PINCH.
 IPR001781; Znf_LIM. 
Pfam
 PF00412; LIM 
SMART
 SM00132; LIM 
PROSITE
 PS00478; LIM_DOMAIN_1
 PS50023; LIM_DOMAIN_2 
PRINTS