UniProt Accession

 NCAM1_MOUSE; P13595; P13594; Q61949; Q61950; Q6LBU8; Q8BQ96; Q8C4B2; Q921P2; Q9R2A7 

Genbank Protein ID

 Y00051; BC011310; AK051197; AK082621; X15049; X15051; X15052; X06328; X07195; X07197; X07198; X07200; X07244 

Genbank Nucleotide ID

 CAA68263.1; AAH11310.1; BAC34554.2; BAC38551.2; CAA33148.1; CAA33150.1; CAA33151.1; CAA29641.1; CAA30173.1; CAA30175.1; CAB40820.1; CAA30177.1; CAA30230.1 

Protein Name

 Neural cell adhesion molecule 1 

Protein Synonyms/Alias

 N-CAM-1; NCAM-1; CD56 

Gene Name

 Ncam1 

Gene Synonyms/Alias

 Ncam 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
1083	EKGPVETKSEPPESE	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. 

Sequence Annotation

 DOMAIN 20 111 Ig-like C2-type 1.
 DOMAIN 116 205 Ig-like C2-type 2.
 DOMAIN 212 302 Ig-like C2-type 3.
 DOMAIN 309 402 Ig-like C2-type 4.
 DOMAIN 407 492 Ig-like C2-type 5.
 DOMAIN 497 596 Fibronectin type-III 1.
 DOMAIN 598 692 Fibronectin type-III 2.
 REGION 152 156 Heparin-binding (Potential).
 REGION 161 165 Heparin-binding (Potential).
 MOD_RES 774 774 Phosphoserine.
 MOD_RES 887 887 Phosphoserine.
 MOD_RES 946 946 Phosphoserine.
 MOD_RES 950 950 Phosphothreonine.
 MOD_RES 952 952 Phosphothreonine.
 MOD_RES 958 958 Phosphoserine.
 MOD_RES 1005 1005 Phosphoserine.
 CARBOHYD 222 222 N-linked (GlcNAc...); partial.
 CARBOHYD 316 316 N-linked (GlcNAc...).
 CARBOHYD 348 348 N-linked (GlcNAc...).
 CARBOHYD 424 424 N-linked (GlcNAc...).
 CARBOHYD 450 450 N-linked (GlcNAc...).
 CARBOHYD 453 453 N-linked (GlcNAc...); atypical.
 CARBOHYD 479 479 N-linked (GlcNAc...).
 DISULFID 41 96
 DISULFID 139 189
 DISULFID 235 288 Probable.
 DISULFID 330 386 Probable.
 DISULFID 427 480 Probable.  

Keyword

 3D-structure; Alternative splicing; Cell adhesion; Cell membrane; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; GPI-anchor; Heparin-binding; Immunoglobulin domain; Lipoprotein; Membrane; Phosphoprotein; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 1115 AA 

Protein Sequence

Gene Ontology

 GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.
 GO:0030424; C:axon; IDA:MGI.
 GO:0009897; C:external side of plasma membrane; IDA:MGI.
 GO:0030426; C:growth cone; IDA:MGI.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0043025; C:neuronal cell body; IDA:MGI.
 GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
 GO:0007166; P:cell surface receptor signaling pathway; IDA:MGI.
 GO:0034109; P:homotypic cell-cell adhesion; IMP:MGI.
 GO:0031175; P:neuron projection development; IGI:MGI.
 GO:0050850; P:positive regulation of calcium-mediated signaling; IDA:MGI.
 GO:0001928; P:regulation of exocyst assembly; IMP:MGI. 

Interpro

 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003598; Ig_sub2.
 IPR009138; Neural_cell_adh. 

Pfam

 PF00041; fn3
 PF07679; I-set 

SMART

 SM00060; FN3
 SM00408; IGc2 

PROSITE

 PS50853; FN3
 PS50835; IG_LIKE 

PRINTS

 PR01838; NCAMFAMILY.