UniProt Accession

 ATPO_DROME; Q24439; Q9VFA4 

Genbank Protein ID

 X99666; AE014297; AY058261 

Genbank Nucleotide ID

 CAA67980.1; AAF55156.1; AAL13490.1 

Protein Name

 ATP synthase subunit O, mitochondrial 

Protein Synonyms/Alias

 Oligomycin sensitivity conferral protein; OSCP 

Gene Name

 Oscp 

Gene Synonyms/Alias

 CG4307 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
55	SQLDQVEKDLTALQA	acetylation	[1]
151	PLDASQSKQLEGALK	acetylation	[1]
158	KQLEGALKSFLKGNE	acetylation	[1]
162	GALKSFLKGNESLKI	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. 

Sequence Annotation

  

Keyword

 ATP synthesis; Complete proteome; Hydrogen ion transport; Ion transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 209 AA 

Protein Sequence

Gene Ontology

 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:FlyBase.
 GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
 GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro. 

Interpro

 IPR000711; ATPase_F1-cplx_OSCP/dsu.
 IPR026015; ATPase_OSCP/delta_N. 

Pfam

 PF00213; OSCP 

SMART

  

PROSITE

 PS00389; ATPASE_DELTA 

PRINTS

 PR00125; ATPASEDELTA.