CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038803
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Sucla2 
Protein Synonyms/Alias
  
Gene Name
 Sucla2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
80VPKGFVAKSSDEAYAacetylation[1]
90DEAYAIAKKLGSKDVacetylation[1]
91EAYAIAKKLGSKDVVacetylation[1]
95IAKKLGSKDVVIKAQacetylation[1]
110VLAGGRGKGTFTSGLacetylation[1]
122SGLKGGVKIVFSPEEacetylation[1]
131VFSPEEAKAVSSQMIacetylation[1]
141SSQMIGQKLITKQTGacetylation[1]
207ENPEAIVKEPVDIIEacetylation[1]
217VDIIEGVKKEQAVTLacetylation[1]
226EQAVTLAKKMGFPSNacetylation[1]
227QAVTLAKKMGFPSNIacetylation[1]
269MVEDADGKVLCMDAKacetylation[1]
364HQVTEAFKLITSDKRacetylation[1]
370FKLITSDKRVQAILVacetylation[1]
419GTRVDDAKALIADSGacetylation[1]
440DDLDEAAKMVVKLSEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 465 AA 
Protein Sequence
MAASMFFGRQ LAAAALRSHR SQTTVRATAQ ALGSSGLFNK HGFQMQQQQQ QQRSLSLHEY 60
LSMELLQEAG VSVPKGFVAK SSDEAYAIAK KLGSKDVVIK AQVLAGGRGK GTFTSGLKGG 120
VKIVFSPEEA KAVSSQMIGQ KLITKQTGAK GRICNQVLVC ERKYPRREYY FAITMERSFQ 180
GPVLIGSSQG GVNIEDVAAE NPEAIVKEPV DIIEGVKKEQ AVTLAKKMGF PSNIVDSAAE 240
NMIKLYNLFL KYDATMVEIN PMVEDADGKV LCMDAKINFD SNSAYRQKKI FALQDWSQED 300
ERDKDAADAD INYIGLDGNI GCLVNGAGLA MATMDIIKLH GGTPANFLDV GGGATVHQVT 360
EAFKLITSDK RVQAILVNIF GGIMRCDIIA QGIVMAVKDL EIRIPVVVRL QGTRVDDAKA 420
LIADSGLKIL ACDDLDEAAK MVVKLSEIVT LAKEAHVDVK FQLPI 465 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:RGD.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IDA:RGD.
 GO:0006105; P:succinate metabolic process; IDA:RGD.
 GO:0006104; P:succinyl-CoA metabolic process; IDA:RGD.
 GO:0006099; P:tricarboxylic acid cycle; IDA:RGD. 
Interpro
 IPR011761; ATP-grasp.
 IPR013650; ATP-grasp_succ-CoA_synth-type.
 IPR013815; ATP_grasp_subdomain_1.
 IPR013816; ATP_grasp_subdomain_2.
 IPR005811; CoA_ligase.
 IPR017866; Succ-CoA_synthase_bsu_CS.
 IPR005809; Succ_CoA_synthase_bsu.
 IPR016102; Succinyl-CoA_synth-like. 
Pfam
 PF08442; ATP-grasp_2
 PF00549; Ligase_CoA 
SMART
  
PROSITE
 PS50975; ATP_GRASP
 PS01217; SUCCINYL_COA_LIG_3 
PRINTS