CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035204
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Nlrp10 
Protein Synonyms/Alias
 RCG39438 
Gene Name
 Nlrp10 
Gene Synonyms/Alias
 rCG_39438 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
444YREGLGIKKLYSFCHacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 669 AA 
Protein Sequence
MALARANSPQ EALLWALNDL EENSFKTLKF HLRDVTQFHL ARGELEGLSQ VDLASKLISM 60
YGAQEAVRVV GRSLQAMNLM ELVDYLNQVC LNDYREIYRE HVLCLEERQD WGVNSSHNKL 120
LLVATSSSGS LRSPSCSDLE QELDPVHVET LFAPEAESYS TPPIVVMQGS AGTGKTTLVK 180
KLVQDWAKGK LYPGQFDYVF YVSCREVVLL PKCDLPNLIC WCCGDDQAPV TEILRQPERL 240
LFILDGYDEL QKSSRAERVL HILMRRREVP CSLLITTRPP ALQSLEPMLG ERRHVHVLGF 300
SEEERETYFC SYFMDKEQLR NALEFVQNNA VLYKACQVPG ICWVVCSWLK GKMARGQEVS 360
ETPSNSTDIF TAYVSTFLPT DGNGDSSELT RHKVLRGLCS LAAEGMRHQR LLFEEDVLRK 420
HSLDGPSLTA FLNCTDYREG LGIKKLYSFC HISFQEFFYA MSFLVKEDQG QLGEATHKEV 480
AKLVDQENYE EVTLSLQFLF DMLKTDNTLS LGLKFCFKIA PSVRQDLKHF KEQVVAIKYN 540
RSWDLEFSLY DSKIKKLKQG IQMKDVIFNV QHSDEKKSGK KKPFSVTSRF GKGPILETGK 600
STRKQKKASN GKSRETEEPP AQDGGKSRLA SRGKGNKEIN DKDGGVYGQE DGEGQEVKKG 660
GEILDEMNG 669 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0019897; C:extrinsic to plasma membrane; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
 GO:0050829; P:defense response to Gram-negative bacterium; IEA:Compara.
 GO:2000778; P:positive regulation of interleukin-6 secretion; IEA:Compara.
 GO:2000484; P:positive regulation of interleukin-8 secretion; IEA:Compara. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR004020; DAPIN.
 IPR011029; DEATH-like_dom.
 IPR007111; NACHT_NTPase.
 IPR027417; P-loop_NTPase. 
Pfam
 PF02758; PYRIN 
SMART
 SM00382; AAA 
PROSITE
 PS50824; DAPIN
 PS50837; NACHT 
PRINTS