CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030317
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Erbb2 interacting protein 
Protein Synonyms/Alias
  
Gene Name
 Erbb2ip 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
101LRELDVSKNGIQEFPubiquitination[1]
381NLSDNRLKNLPFSFTubiquitination[1]
492TPYPDELKNMVKTVQubiquitination[1]
496DELKNMVKTVQTIVHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Leucine-rich repeat; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1450 AA 
Protein Sequence
MTTKRSLFVR LVPCRCLRGE EETVTTLDYS HCSLEQVPKE IFTFEKTLEE LYLDANQIEE 60
LPKQLFNCQS LHKLSLPDND LTTLPASIAN LINLRELDVS KNGIQEFPEN IKNCKVLTIV 120
EASVNPISKL PDGFSQLLNL TQLYLNDAFL EFLPANFGRL TKLQILELRE NQLKMLPKTM 180
NRLTQLERLD LGSNEFTEVP EVLEQLSGLR EFWMDGNRLT FIPGFIGSLR QLTYLDVSKN 240
NIEMVEEGIS TCENLQDFLL SSNSLQQLPE TIGSLKNVTT LKIDENQLMY LPDSIGGLRS 300
IEELDCSFNE IEALPSSIGQ LTNMRTFAAD HNYLQQLPPE IGNWKNITVL FLHCNKLETL 360
PEEMGDMQKL KVINLSDNRL KNLPFSFTKL QQLTAMWLSD NQSKPLIPLQ KETDTETQKM 420
VLTNYMFPQQ PRTEDVMFIS DNESFNPALW EEQRKQRAQV AFECDEDKDE REAPPREGNL 480
KRYPTPYPDE LKNMVKTVQT IVHRLKDEET NEESGRDLKQ HEDQQVVNKD KCVKTSESTT 540
TKSKLDEREK YMNSVQKMSE PEAETNGGNL PVTASMKLSG NLKHIVNHDD VFEESEELSS 600
DEEMKMAEMR PPLIESSINQ PKVVALSNNK KDDAKDADSL SDEVTHNSNQ NNSNCSSPSR 660
MSDSVSLNTD SSQDTSLCSP VKQTPVDSNS KVRQEDENFN SLLQNGVNLN NSPEEKFKIN 720
DKKDFKLPEY DLNIEEQLVL IEKDIDSKAT SDDSRQLDHI NMNINKLVTN NIFQPEVMER 780
SKMQDIVLGT GFLSIHPKNE AEHIENGAKF PNLESINKVN GLCEDTAPSP GRVEPQKASS 840
SADVGISKST EDLSPQRSGP TGAVVKSHSI TNMETGGLKI YDILGDDGPQ PPSAAVKIAS 900
AVDGKNIVRS KSATLLYDQP LQVFTAASSS SELLSGTKAV FKFDSNHNPE EPDIIRAATV 960
SGPQSTPHLY GPPQYNVQYS GSATVKDTLW HPKQNPQIDP VSFPPQRLPR SESAENHSYA 1020
KHSANMNFSN HNNVRANTGY HLQQRLAPAR HGEMWAISPN DRLVPAVTRT TIQRQSSVSS 1080
TASVNLGDPT RRTEGDYLSY RELHSMGRTP VMSGSQRPLS ARAYSIDGPN TSRPQSARPS 1140
INEIPERTMS VSDFNYSRTS PSKRPNTRVG SEHSLLDPPG KSKVPHDWRE QVLRHIEAKK 1200
LEKSMLSRSF NSNLTAVSSS HYGSSRDLHG SQGSLALSVA DGRGSGGHIF RHPQTSSPGE 1260
CCQDDRFMSE EQNHPSGALS HRGLPDSLMK MPLSNGQMGQ PLRPQAHYSQ THHPPQASVA 1320
RHPSREQLID YLMLKVAHQP PYTHPHCSPR QGHELAKQEI RVRVEKDPEL GFSISGGVGG 1380
RGNPFRPDDD GIFVTRVQPE GPASKLLQPG DKIIQANGYS FINIEHGQAV SLLKTFHNAV 1440
DLIIVREVSS 1450 
Gene Ontology
 GO:0016323; C:basolateral plasma membrane; IDA:MGI.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0030056; C:hemidesmosome; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0006605; P:protein targeting; IDA:MGI. 
Interpro
 IPR001611; Leu-rich_rpt.
 IPR025875; Leu-rich_rpt_4.
 IPR001478; PDZ. 
Pfam
 PF12799; LRR_4
 PF00595; PDZ 
SMART
 SM00228; PDZ 
PROSITE
 PS51450; LRR
 PS50106; PDZ 
PRINTS